We prove that arbitrary homomorphisms from one of the groups Homeo(2 N ), Homeo(2 N ) N , Aut(Q, <), Homeo(R), or Homeo(S 1 ) into a separable group are automatically continuous. This has consequences for the representations of these groups as discrete groups. For example, it follows, in combination with a result on V.G. Pestov, that any action of the discrete group Homeo+(R) by homeomorphisms on a compact metric space has a fixed point.