Frankincense Tree Physiology and Its Responses to Wounding Stress

Al‐Harrasi, Ahmed; Khan, Abdul Latif; Asaf, Sajjad; Al‐Rawahi, Ahmed

doi:10.1007/978-3-030-16725-7_4

Cited by 2 publications

(2 citation statements)

References 71 publications

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“…In addition, the HMBC spectrum showed the correlation between H-1′ and C-28, which suggested that the sugar moiety linked to C-28. It must be noted that a large number of literature examples have confirmed that the biosynthesis of the historic precursor β-amyrin commences at the chair–chair–chair–boat conformation of 2,3-oxidosqualene. − This conformation was the only one that existed in nature. − This conformation allows it to cyclize to the corresponding 6.6.6.5-fused tetracyclic dammarenyl cation . Thus, the absolute configurations of C-10, C-9, C-5, C-8, C-14, C-17 in all pentacyclic triterpenoid have been determined in earlier literature.…”

Section: Results and Discussionmentioning

confidence: 97%

Pentacyclic Triterpenoid Saponins, Poterinasides A–J, from Silverweed Cinquefoil Roots Promising Hepatoprotective and Anti-inflammatory Agents

et al. 2021

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Silverweed cinquefoil roots, as dietary supplements, foods, and medicines, are widely used in western areas of China, specifically in Tibet Autonomous Region and Gansu and Qinghai Provinces. In this paper, 10 new natural pentacyclic triterpenoid saponins (1−10), named poterinasides A−J, along with 14 known compounds (11−24) were isolated and purified from silverweed cinquefoil roots. The chemical structures of 1−10 were established by extensive analysis of 1D and 2D NMR data and mass spectrometric data. Poterinasides A (1), B (2), and G (7) with the unique position of substituents on the E ring had never been discovered in natural products before.

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Section: Results and Discussionmentioning

confidence: 97%

Pentacyclic Triterpenoid Saponins, Poterinasides A–J, from Silverweed Cinquefoil Roots Promising Hepatoprotective and Anti-inflammatory Agents

et al. 2021

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“…For centuries, frankincense (olibanum) extracted from the Boswellia tree, mainly from B. serrata , has been used as a source of BAs. Other species studied included B. sacra, B. papyrifera , and B. carteri , which are also used as BA sources worldwide ( Al-Harrasi et al, 2019 ; Bongers et al, 2019 ). The resin of the Boswellia tree is composed of essential oil (5%–9%) and mucilage (6%–20%), the major component of the BAs, which has been quantified around 25%–35% of the resin acid mixture ( Ennet, 2000 ; Al-Harrasi et al, 2021 ).…”

Section: General Characterization Of Boswellic Acid and Its Semi-synt...mentioning

confidence: 99%

Anti-cancer properties of boswellic acids: mechanism of action as anti-cancerous agent

Trivedi

Soni²,

Dhyani

et al. 2023

Front. Pharmacol.

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With the advent of highly effective plant-based medications with few or no side effects, the use of phytomedicines against complex diseases such as cancer is becoming more widespread. The broadly recognized pentacyclic triterpenes known as boswellic acids (BAs) are derived from the oleogum resin, or frankincense, extracted from the plant species of the genus Boswellia. The frankincense mixture contains various BA types, each having a different potential and helping treat certain cancers. This review focuses on details regarding the traits of the BAs, their roles as anti-cancer agents, the mechanism underlying their activities, and the function of their semi-synthetic derivatives in managing and treating certain cancers. The review also explores the biological sources of BAs, how they are conserved, and how biotechnology might help preserve and improve in vitro BA production. The review concludes that the BAs and their semi-synthetic derivatives are effective against a broad spectrum of cancer cell lines. The detailed information in the review can be helpful for researchers to gain more information about BAs and BA-based medications for efficient and cost-effective cancer treatments.

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Frankincense Tree Physiology and Its Responses to Wounding Stress

Cited by 2 publications

References 71 publications

Pentacyclic Triterpenoid Saponins, Poterinasides A–J, from Silverweed Cinquefoil Roots Promising Hepatoprotective and Anti-inflammatory Agents

Pentacyclic Triterpenoid Saponins, Poterinasides A–J, from Silverweed Cinquefoil Roots Promising Hepatoprotective and Anti-inflammatory Agents

Anti-cancer properties of boswellic acids: mechanism of action as anti-cancerous agent

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