Free-breathing pseudo-golden-angle bSSFP cine cardiac MRI for biventricular functional assessment in congenital heart disease

Kravchenko, Dmitrij; Isaak, Alexander; Zhang, Shuo; Katemann, Christoph; Mesropyan, Narine; Bischoff, Leon; Pieper, Claus Christian; Kuetting, Daniel; Attenberger, Ulrike I.; Weber, O.; Hart, Christopher; Luetkens, Julian A.

doi:10.1016/j.ejrad.2023.110831

Cited by 2 publications

(1 citation statement)

References 29 publications

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“…We recommend that ‘breath‐holding’ as a term be employed with caution, recognizing that it has power as a lay term, but also has somewhat restricted meaning to the physiologist. ‘Intermittent breathing’ with periods of apnoea is a more appropriate term when describing an overall ventilatory pattern, while ‘breath‐holding’ can effectively be used to describe a certain state at a certain time such as the procedural instruction to human patients undergoing diagnostic testing (Kravchenko et al., 2023 ; Ma et al., 2019 ) or its use in breath‐hold diving in humans (Patrician et al., 2021 ; Tetzlaff et al., 2021 ).…”

Section: Commonly Used Scientific Terminology Associated With Intermi...mentioning

confidence: 99%

Breathing patterns and associated cardiovascular changes in intermittently breathing animals: (Partially) correcting a semantic quagmire

Burggren,

Fahlman,

Milsom

2024

Experimental Physiology

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Many animal species do not breathe in a continuous, rhythmic fashion, but rather display a variety of breathing patterns characterized by prolonged periods between breaths (inter‐breath intervals), during which the heart continues to beat. Examples of intermittent breathing abound across the animal kingdom, from crustaceans to cetaceans. With respect to human physiology, intermittent breathing—also termed ‘periodic’ or ‘episodic’ breathing—is associated with a variety of pathologies. Cardiovascular phenomena associated with intermittent breathing in diving species have been termed ‘diving bradycardia’, ‘submersion bradycardia’, ‘immersion bradycardia’, ‘ventilation tachycardia’, ‘respiratory sinus arrhythmia’ and so forth. An examination across the literature of terminology applied to these physiological phenomena indicates, unfortunately, no attempt at standardization. This might be viewed as an esoteric semantic problem except for the fact that many of the terms variously used by different authors carry with them implicit or explicit suggestions of underlying physiological mechanisms and even human‐associated pathologies. In this article, we review several phenomena associated with diving and intermittent breathing, indicate the semantic issues arising from the use of each term, and make recommendations for best practice when applying specific terms to particular cardiorespiratory patterns. Ultimately, we emphasize that the biology—not the semantics—is what is important, but also stress that confusion surrounding underlying mechanisms can be avoided by more careful attention to terms describing physiological changes during intermittent breathing and diving.

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Section: Commonly Used Scientific Terminology Associated With Intermi...mentioning

confidence: 99%

Breathing patterns and associated cardiovascular changes in intermittently breathing animals: (Partially) correcting a semantic quagmire

Burggren,

Fahlman,

Milsom

2024

Experimental Physiology

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Deep learning super-resolution reconstruction for fast and high-quality cine cardiovascular magnetic resonance

Kravchenko,

Isaak,

Mesropyan

et al. 2024

Eur Radiol

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Objectives To compare standard-resolution balanced steady-state free precession (bSSFP) cine images with cine images acquired at low resolution but reconstructed with a deep learning (DL) super-resolution algorithm. Materials and methods Cine cardiovascular magnetic resonance (CMR) datasets (short-axis and 4-chamber views) were prospectively acquired in healthy volunteers and patients at normal (cineNR: 1.89 × 1.96 mm2, reconstructed at 1.04 × 1.04 mm2) and at a low-resolution (2.98 × 3.00 mm2, reconstructed at 1.04 × 1.04 mm2). Low-resolution images were reconstructed using compressed sensing DL denoising and resolution upscaling (cineDL). Left ventricular ejection fraction (LVEF), end-diastolic volume index (LVEDVi), and strain were assessed. Apparent signal-to-noise (aSNR) and contrast-to-noise ratios (aCNR) were calculated. Subjective image quality was assessed on a 5-point Likert scale. Student’s paired t-test, Wilcoxon matched-pairs signed-rank-test, and intraclass correlation coefficient (ICC) were used for statistical analysis. Results Thirty participants were analyzed (37 ± 16 years; 20 healthy volunteers and 10 patients). Short-axis views whole-stack acquisition duration of cineDL was shorter than cineNR (57.5 ± 8.7 vs 98.7 ± 12.4 s; p < 0.0001). No differences were noted for: LVEF (59 ± 7 vs 59 ± 7%; ICC: 0.95 [95% confidence interval: 0.94, 0.99]; p = 0.17), LVEDVi (85.0 ± 13.5 vs 84.4 ± 13.7 mL/m2; ICC: 0.99 [0.98, 0.99]; p = 0.12), longitudinal strain (−19.5 ± 4.3 vs −19.8 ± 3.9%; ICC: 0.94 [0.88, 0.97]; p = 0.52), short-axis aSNR (81 ± 49 vs 69 ± 38; p = 0.32), aCNR (53 ± 31 vs 45 ± 27; p = 0.33), or subjective image quality (5.0 [IQR 4.9, 5.0] vs 5.0 [IQR 4.7, 5.0]; p = 0.99). Conclusion Deep-learning reconstruction of cine images acquired at a lower spatial resolution led to a decrease in acquisition times of 42% with shorter breath-holds without affecting volumetric results or image quality. Key Points QuestionCine CMR acquisitions are time-intensive and vulnerable to artifacts. FindingsLow-resolution upscaled reconstructions using DL super-resolution decreased acquisition times by 35–42% without a significant difference in volumetric results or subjective image quality. Clinical relevanceDL super-resolution reconstructions of bSSFP cine images acquired at a lower spatial resolution reduce acquisition times while preserving diagnostic accuracy, improving the clinical feasibility of cine imaging by decreasing breath hold duration. Graphical Abstract

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Free-breathing pseudo-golden-angle bSSFP cine cardiac MRI for biventricular functional assessment in congenital heart disease

Cited by 2 publications

References 29 publications

Breathing patterns and associated cardiovascular changes in intermittently breathing animals: (Partially) correcting a semantic quagmire

Breathing patterns and associated cardiovascular changes in intermittently breathing animals: (Partially) correcting a semantic quagmire

Deep learning super-resolution reconstruction for fast and high-quality cine cardiovascular magnetic resonance

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