2017
DOI: 10.24953/turkjped.2017.01.008
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Free estradiol index levels associated with high sensitivity CRP levels in male children

Abstract: Ağırbaşlı M, Tanrıkulu A, Azizy M. Free estradiol index levels associated with high sensitivitiy CRP levels in male children. Turk J Pediatr 2017; 59: 49-55. Biomarkers of inflammation such as high-sensitivity C-reactive protein (hs-CRP) associate with subclinical atherosclerosis. Atherosclerosis is an early onset disease in life. Sex hormones and puberty modulate metabolism in children. Studies indicate that low sex hormone binding globulin (SHBG) levels associate with insulin resistance and metabolic syndrom… Show more

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(1 citation statement)
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“…The association of CRP levels with sex steroids and with the circulating glycoprotein involved in their transportation, sex hormone‐binding globulin (SHBG), has also been investigated in some studies in children. Negative associations of CRP with testosterone levels in obese males 16 and positive association with estradiol 17 have been reported and its association with SHBG 18,19 . However, the studies in children are scarce and, to our knowledge, the relationship of sex steroids with CRP concentrations has not been investigated in a general population of Caucasian adolescents.…”
Section: Introductionmentioning
confidence: 99%
“…The association of CRP levels with sex steroids and with the circulating glycoprotein involved in their transportation, sex hormone‐binding globulin (SHBG), has also been investigated in some studies in children. Negative associations of CRP with testosterone levels in obese males 16 and positive association with estradiol 17 have been reported and its association with SHBG 18,19 . However, the studies in children are scarce and, to our knowledge, the relationship of sex steroids with CRP concentrations has not been investigated in a general population of Caucasian adolescents.…”
Section: Introductionmentioning
confidence: 99%