Abstract. In this paper we consider a refinement, due to Nathanson, of the Calkin-Wilf tree. In particular, we study the properties of such trees associated with the matrices Lu = 1 0 u 1 and Rv = 1 v 0 1 , where u and v are nonnegative integers. We extend several known results of the original Calkin-Wilf tree, including the symmetry, numeratordenominator, and successor formulas, to this new setting. Additionally, we study the ancestry of a rational number appearing in a generalized Calkin-Wilf tree.