Background: Bone giant cell tumors are rarely found on the hand. Several treatments have been described but only the resection/ amputation of the affected segment can offer an effective cure in advanced cases. Various forms of reconstruction have been described, namely using a free graft of fibula. Case Report: The authors present a case of a man with an osteolytic and expansive lesion of the distal end of the second metacarpal that was treated with resection and autologous free fibular graft with good clinical and radiologic outcome. Conclusion: Free fibular graft is a possible solution to avoid ray amputation in cases of bone tumors in the metacarpals.