Free Radical Scavenging Activities of Polyphenolic Compounds Isolated from Medicago sativa and Medicago truncatula Assessed by Means of Thin‐layer Chromatography DPPH˙ Rapid Test

Abstract

A simple, rapid and reliable TLC-DPPH˙ test with image processing has been developed enabling comparison of free radical scavenging activity of plant polyphenols. The influence of different structural features on the observed activity was measured successfully.

Nephroprotective Effect of Nasturtium Officinale (Watercress) Ethanol Extract and Vitamin E on Vancomycin-Induced Nephrotoxicity in Rats

“…In our earlier study we found that NOE exhibited a noticeable anti-inflammatory activity in several animal models of inflammation (17). Moreover, free radical scavenging properties of phenolic and flavonoid compounds were confirmed in some studies (37)(38)(39). In this study, phenolic and flavonoid contents of NOE detected to be 71 ± 6.23 gallic acid equivalents/g dried extract and 95.26 ± 7.6 mg rutin equivalents/g dried extract, respectively.…”

LC–MS guided isolation, quantification and antioxidant evaluation of bioactive principles from Epimedium elatum

“…The SAR antioxidant studies of flavonoids have been a subject of number of research proposals [36]. Free hydroxyl groups at C-3 and C-4 positions, C2 C3 double bond, C-3 and C-4 dihydroxy groups are the necessary structural requirements for better antioxidant activity of the flavonoid [36]. Moreover, in case of prenylated flavonoids, the position of prenyl groups on the flavonoid skeleton plays a significant role in imparting antioxidant activity [37].…”

“…Flavonoids which produce relatively stable resulting antioxidant radicals can quickly terminate radical chain reaction, and may be considered as effective antioxidants. The SAR antioxidant studies of flavonoids have been a subject of number of research proposals [36]. Free hydroxyl groups at C-3 and C-4 positions, C2 C3 double bond, C-3 and C-4 dihydroxy groups are the necessary structural requirements for better antioxidant activity of the flavonoid [36].…”

“…Dibenzylideneacetone (DBA) is being reported for the first time from any plant source. It induces apoptosis in mucoepidermoid carcinomas (MEC) [36]. …”

Novel Flavonol Glycosides from the Aerial Parts of Lentil (Lens culinaris)

“…The ability of lentil flavonoids to scavenge DPPH radicals was determined using a TLC rapid test [35]. Briefly, standard solutions (1 mg·mL ) of the purified flavonoids and rutin (positive control) were prepared.…”