Free radical scavenging activity of different extracts and some constituents from the leaves of Ligustrum vulgare and L. delavayanum

Nagy, Milan; Spilková, Jiřina; Vrchovská, Vendula; Kontšeková, Z.; Šeršeň, F.; Mučaji, Pavel; Grančai, D

doi:10.1016/j.fitote.2006.04.010

Cited by 18 publications

(13 citation statements)

References 5 publications

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“…The IC 50 values for L. morrisonense, L. liukiuense, L. pricei, L. sinense, and L. lucidum in the DPPH assay were 0.48, 0.94, 1.38, 1.47, and 2.06 mg/ml, respectively. The results obtained from the DPPH assay is similar to recent reports of other Ligustrum species, including L. lucidum and L. robustum (Chen, Wong, Leung, He, & Huang, 2002;Katsube et al, 2004;Nagy et al, 2006;She, Wang, Zeng, Yang, & Zhang, 2008;Zhu et al, 2009). For the TEAC assay, the IC 50 values for L. morrisonense, L. liukiuense, L. pricei, L. sinense, and L. lucidum were 0.21, 0.24, 0.37, 0.52, and 1.40 mg/ml, respectively.…”

Section: Antioxidant and Radical-scavenging Activity Of Ligustrum Leavessupporting

confidence: 87%

“…Phenylpropanoids are the intermediate compounds in the biosynthesis of flavonoids and some phenolic compounds, and they also possess antioxidant activities (Korkina, 2007). Moreover, several phytochemical reports point to the antioxidant and anti-mutagenic activity of some phenylethanoids, flavonoids, and secoiridoids isolated from the genus Ligustrum (He et al, , 2003Nagy et al, 2006Nagy et al, , 2009Wong et al, 2001). Thus, the total phenolic, flavonoid, and phenylpropanoid Fig.…”

Section: Quantification Of Phytochemical Profiles In Ligustrum Leavesmentioning

confidence: 99%

“…Since ROS play an important role in intracellular oxidative damage, effects of methanol extracts from the aforementioned Ligustrum leaves on the scavenging activities of superoxide anions were evaluated, hydrogen peroxide (H 2 O 2 ) and hydroxyl radicals, the inhibition of lipid peroxidation induced by the Fenton reaction and the erythrocyte haemolysis caused by the peroxyl radical 2,2 0 -azobis(2-amidinopropane) dihydrochloride (AAPH). Based on phytochemical reports on the genus Ligustrum (He et al, , 2003Nagy et al, 2006Nagy et al, , 2009Wong et al, 2001), the amounts of total phenolics, flavonoids, phenylpropanoids, and iridoids in the methanol extracts from the aforementioned Ligustrum leaves were determined by spectrophotometry.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the antioxidant activity of five endemic Ligustrum species leaves from Taiwan flora in vitro

Wu¹,

Lin²,

Hseu³

et al. 2011

Food Chemistry

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Section: Antioxidant and Radical-scavenging Activity Of Ligustrum Leavessupporting

confidence: 87%

Section: Quantification Of Phytochemical Profiles In Ligustrum Leavesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of the antioxidant activity of five endemic Ligustrum species leaves from Taiwan flora in vitro

Wu¹,

Lin²,

Hseu³

et al. 2011

Food Chemistry

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“…i) The scavenging of DPPH radicals was carried out in the methanol and chloroform solutions according to Nagy et al (2006). Briefly: Various amounts of studied compounds were added to DPPH solution, so that the final DPPH concentration was always 7 × 10 -5 mol/dm 3 .…”

Section: Methodsmentioning

confidence: 99%

Antioxidative effect of some hydroxy substituted aromatic bisimines

Šeršeň¹,

Walko²,

Loos³

2009

gpb

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Abstract. This work deals with antioxidative properties of some derivatives 4,4'-bis(dihydroxybenzylanilidenamino)diphenylmethanes and diphenylethers, which structure is similar to resveratrol. Four derivatives of above-mentioned compounds were synthesized with hydroxyl (OH) groups in various positions. It was found that derivatives with two OH groups in 2 and 5 positions were very good scavengers of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in both methanol and chloroform. On the other hand derivatives with OH groups in positions 2 and 4 did not scavenge DPPH radicals. The calculation of free enthalpies (by quantum chemical method AM1) necessary for the formations of anions or radicals support above mentioned findings because the enthalpies for effective derivatives were lesser, than for ineffective ones. Also, it was found that studied compounds did not scavenge hydroxyl radicals whereas resveratrol did it.

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“…The activity was expressed as SC 50 (µg.ml -1 ), which is the concentration of the test solution required to give a 50% decrease in absorbance from that of a blank solution (Lamaison et al, 1990(Lamaison et al, , 1991, (Nagy et al, 2006). Trolox, ascorbic acid and rosmarinic acid were used as a positive control.…”

Section: )mentioning

confidence: 99%

The content of phenolic compounds in underground and aerial parts of different Mentha species

Fialová

Tekeľová

Grančai

2012

Acta Facultatis Pharmaceuticae Universitatis Comenianae

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Mentha L., the genus belonging to family Lamiaceae, subfamily Nepetoidae, has high commercial importance in the pharmacy as well as in food industry. Mints are available in all five continents and are important sources of each traditional medicine in the prevention and therapy of plenty of diseases. The most active compounds are essential oil and polyphenols. In the past the secondary metabolites in aerial parts were examined, but there is no evidence about the determination of secondary metabolites in underground parts of mints. Therefore the object of this work was to determine the content of phenolic compounds (total hydroxycinnamic derivatives (THD) and flavonoids) of methanol extracts of rhizomes of different Mentha L. and their comparison with leaves extracts. The contents of secondary metabolites were determined using spectrophotometric methods of Slovak Pharmacopoeia. We have detected similar quantities of THD in leaves (0.79 -2.48 %) and rhizomes (0.96 -2.18 %), but underground parts were poor in content of flavonoids (< 0.1 %). The free radical scavenging activity using DPPH free radical was investigated as well. A bit stronger antioxidant activity was shown in leaves extracts considering flavonoids content.

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Free radical scavenging activity of different extracts and some constituents from the leaves of Ligustrum vulgare and L. delavayanum

Cited by 18 publications

References 5 publications

Evaluation of the antioxidant activity of five endemic Ligustrum species leaves from Taiwan flora in vitro

Evaluation of the antioxidant activity of five endemic Ligustrum species leaves from Taiwan flora in vitro

Antioxidative effect of some hydroxy substituted aromatic bisimines

The content of phenolic compounds in underground and aerial parts of different Mentha species

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