Free Radical Scavenging Activity of Some Therapeutic Plants and Protection of Radiation-induced DNA Damage by
            <i>Zingiber montanum</i>
            Extract

Thokchom, Dhanaraj Singh; Sharma, G. J.

doi:10.1080/10496475.2011.637608

Cited by 4 publications

(2 citation statements)

References 47 publications

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“…The complex curcuminoids, cassumunins A, B, and C, isolated from acetone extract of Z. montanum rhizomes, exhibited more potent antioxidant and anti-inflammatory properties than curcumin [8]. Methanol extract from Z. montanum displayed DPPH radical scavenging activity with a half maximal inhibitory concentration (IC50) value of 0.34 mg/mL [9]. The volatile oils of some Zingiber plants displayed multiple biological activities, including antioxidant effects [10].…”

Section: Introductionmentioning

confidence: 99%

Effect of Extraction Solvents on Antioxidant and Antibacterial Activity of Zingiber montanum Rhizomes

Thepthong,

Rattakarn,

Ritchaiyaphum

et al. 2023

ASEAN Sci Tech Rept

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The Zingiber montanum rhizome has been utilized for its antiviral, immunomodulatory, anti-inflammatory, and antibacterial properties for a long time, particularly in Malaysia, Indonesia, and Thailand. Additionally, the rhizome has been a traditional ingredient in Asian cosmetic products. This study aimed to investigate the impact of different extracting solvents (hexane, dichloromethane, acetone, ethanol, methanol, 50% ethanol, and 75% ethanol) on the phenolic content, as well as the antioxidant and antibacterial activities of Zingiber montanum. The antioxidant activity was evaluated using two methods: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay and ferric-reducing antioxidant power (FRAP) assay, while antibacterial activity was tested against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa strains. The methanol extract demonstrated the highest phenolic content, while the ethanol extract exhibited a slightly lower amount. In the DPPH assay, the methanol extract showed an IC50 value of 36.89 ± 2.53 µg/mL, whereas the ethanol extract displayed a marginally higher value of 38.89 ± 0.27 µg/mL. In terms of ferric-reducing antioxidant power, the ethanol extract had slightly higher FRAP values (78.65 ± 4.73 mg AAE/g) than the methanol extract (76.09 ± 4.57 mg AAE/g). All extracts exhibited low activity against the three tested bacterial strains. Ethanol extract demonstrated the most antibacterial activity, with a clear zone ranging from 10.50 to 12.00 mm. The results suggest that ethanol is a suitable solvent for extracting Zingiber montanum rhizome for value-added materials application for cosmetic products.

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Section: Introductionmentioning

confidence: 99%

Effect of Extraction Solvents on Antioxidant and Antibacterial Activity of Zingiber montanum Rhizomes

Thepthong,

Rattakarn,

Ritchaiyaphum

et al. 2023

ASEAN Sci Tech Rept

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“…The extracts from Z. montanum showed inhibition of metal ions, including CuCl 2 , CoCl 2 , HgCl 2 and ZnCl 2 (Jamir and Seshagirirao, 2018). Thokchom and Sharma (2012) reported that methanol extract from Z. montanum displayed DPPH • radical scavenging activity with a half maximal inhibitory concentration (IC 50 ) value of 0.34 mg/mL. In addition, Z. montanum extract exhibited a high DNA protection rate of 81.87%.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and anti-aging enzyme activities of bioactive compounds isolated from selected Zingiberaceae plants

2021

ANRES

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Bioactive compounds and antioxidant and enzyme inhibition activity levels were evaluated for three plants in the Zingiberaceae family in Thailand. Quantification of the phenolic and curcumin contents revealed that the largest component of all extracts was phenolic compounds (213.16-317.64 mg/g extract). The major curcuminoids in Curcuma longa L., Curcuma aromatica Salisb. and Zingiber montanum (J.Koenig) Link ex A.Dietr. were bisdemethoxycurcumin (BDMC; 27.31 mg/g extract), curcumin (16.59 mg/g extract), and curcumin (0.12 mg/g extract), respectively. The extracts from C. longa, C. aromatica and Z. montanum all showed antioxidant activity that was assessed using 1,1-diphenyl-2-picrylhydrazyl radical 2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydrazyl (DPPH • ) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS •+ ) radical scavenging assay. In addition, all extracts had copper chelating activity of more than 50%, with the extract from C. longa having the highest chelating activity (76.45%). All extracts from the three plants inhibited tyrosinase and elastase activity with half maximal inhibitory concentration values of 290.33-1,373.68 µg/mL and 69.61-3386.23 µg/mL, respectively. In addition, collagenase inhibition activity was observed in all extracts. The findings from this study showed that extracts from C. longa, C. aromatica and Z. montanum have potential antioxidant activity and can act as anti-tyrosinase, anti-collagenase and anti-elastase agents. The extracts could be further applied in cosmeceuticals as an active ingredient for anti-aging products.

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Zabetian¹,

Sahraei²,

Hakimelahi³

et al.

106

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Free Radical Scavenging Activity of Some Therapeutic Plants and Protection of Radiation-induced DNA Damage by Zingiber montanum Extract

Cited by 4 publications

References 47 publications

Effect of Extraction Solvents on Antioxidant and Antibacterial Activity of Zingiber montanum Rhizomes

Effect of Extraction Solvents on Antioxidant and Antibacterial Activity of Zingiber montanum Rhizomes

Antioxidant and anti-aging enzyme activities of bioactive compounds isolated from selected Zingiberaceae plants

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