In this paper, the free vibration of the thick annular sector plate on Pasternak foundation with general boundary conditions is presented by using the three-dimensional elasticity theory and the improved Fourier series method. The displacements of the thick annular sector plate are expanded to be the three-dimensional (3-D) Fourier cosine series supplemented with several auxiliary functions to eliminate all the relevant discontinuities of the displacements and their derivatives at the edges with general boundary conditions. This method can be universally applied to any kinds of classical boundaries, elastic boundaries and the combinations of both boundaries without any special change in the solution procedure. The excellent accuracy and reliability of the current solutions are demonstrated by numerical examples and comparison of the present results with those available in the literature. Furthermore, numerous new results for thick annular sector plates on Pasternak foundation with general elastic restrains are presented. In addition, comprehensive studies on the effects of the elastic restraint parameters, geometric parameters and elastic foundation coefficients are also reported.