2004
DOI: 10.2754/avb200473030375
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Freemartinism: Three Cases in Goats

Abstract: Szatkowska I., Zych S., Uda∏a J., Dybus A., B∏aszczyk P., P. Sysa, Dàbrowski T: Freemartinism: Three Cases in Goats. Acta Vet Brno 2004, 73: 375-378.The aim of the study was a molecular and cytogenetic analysis of three cases of caprine freemartinism. The objects of the study were three White Improved goats culled due to infertility. The SRY gene was treated as a marker of presence (or absence) of the Y chromosome in the population of the blood nuclear cells carrying XY heterochromosomes, which occurs in a fem… Show more

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Cited by 9 publications
(6 citation statements)
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“…6 Enlarged abdominal structures from male genital origin, compatible with neoplasia, have also been described in caprine chimeras. 9 Since Leydig cells secrete testosterone, they may be responsible for the hyperandrogenism symptoms observed in this case. Leydig cells appear to be active in 3month-old XX PIS kids, ensuring testosterone secretion from an early age.…”
mentioning
confidence: 82%
“…6 Enlarged abdominal structures from male genital origin, compatible with neoplasia, have also been described in caprine chimeras. 9 Since Leydig cells secrete testosterone, they may be responsible for the hyperandrogenism symptoms observed in this case. Leydig cells appear to be active in 3month-old XX PIS kids, ensuring testosterone secretion from an early age.…”
mentioning
confidence: 82%
“…In consequence, the genital system of a female twin becomes masculinized. Sporadic cases of freemartinism have been also observed in goats, but with low frequency, not exceeding 1% (3,4).…”
Section: Introductionmentioning
confidence: 99%
“…Among other ruminants, freemartinism was quite extensively studied in sheep, and the incidence of this DSD, diagnosed by a chromosome study, was around 5% XX/XY [40,41]. Studies in goats also indicate that the frequency of freemartins is similar to that in sheep [42].…”
Section: Xx/xy Lymphocyte Chimerismmentioning
confidence: 97%