2013
DOI: 10.1177/1938640013510314
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Freiberg’s Infraction

Abstract: Freiberg's infraction is a condition of cartilage degeneration of the lesser metatarsal heads. Adolescent females are the "textbook" patients but both males and females may present with this condition later in life. The second and third metatarsals are the most commonly affected, while involvement of the fourth and fifth is rare. The incidence is higher in females than in males. The pathophysiology is unknown, but studies suggest a combination of vascular compromise, genetic predisposition, and altered biomech… Show more

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Cited by 46 publications
(18 citation statements)
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“…Bone scan and magnetic resonance imaging (MRI) may be useful early in the disease process before radiographic changes are evident, the latter being particularly useful as an early detector of progressive joint degeneration [19]. In our case however, the CT images played an essential role for the definitive diagnosis, showing the necrosis of the metatarsal head, the joint surface degeneration and the bone fragments, otherwise hidden by the external bony shell.…”
Section: Discussionmentioning
confidence: 80%
“…Bone scan and magnetic resonance imaging (MRI) may be useful early in the disease process before radiographic changes are evident, the latter being particularly useful as an early detector of progressive joint degeneration [19]. In our case however, the CT images played an essential role for the definitive diagnosis, showing the necrosis of the metatarsal head, the joint surface degeneration and the bone fragments, otherwise hidden by the external bony shell.…”
Section: Discussionmentioning
confidence: 80%
“…In Freiberg's disease, there is avascular necrosis of the metatarsal head, most frequently of the second metatarsal bone (in 68% of cases). It is related to chronic repetitive trauma, systemic diseases (such as diabetes and systemic lupus erythematosus), and mechanical factors (such as the second metatarsal syndrome) ( 7 ) . It predominantly affects young women and manifests as pain and swelling of the metatarsophalangeal joints of the second toe ( 7 ) .…”
Section: Discussionmentioning
confidence: 99%
“…It is related to chronic repetitive trauma, systemic diseases (such as diabetes and systemic lupus erythematosus), and mechanical factors (such as the second metatarsal syndrome) ( 7 ) . It predominantly affects young women and manifests as pain and swelling of the metatarsophalangeal joints of the second toe ( 7 ) . The radiological findings vary depending on the stage of the disease.…”
Section: Discussionmentioning
confidence: 99%
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“…Fracture or injury to the supporting structures of the MTP joint (plantar plate and collateral ligaments) deteriorates the foot’s biomechanical alignment, leading to forefoot instability and pain [6]. Other conditions, including hallux rigidus, Morton’s neuroma, tarsal tunnel syndrome, Freiberg infarction, and chronic inflammatory diseases can increase forefoot load without direct load on the MT [8,11-13].…”
Section: Metatarsalgiamentioning
confidence: 99%