Frequência da deficiência de glicose-6-fosfato desidrogenase (G-6-PD) e sua relação com a icterícia neonatal

Iglessias, Marli Auxiliadora C.

doi:10.1590/s1516-84842009000100019

Cited by 2 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The main cause of neonatal jaundice in G6PD-deficient infants is the inability of the liver to conjugate bilirubin properly, thereby exacerbating the bilirubinemia. (5) The study by Iglessias et al (6) presented in this issue shows that 3.0% of newborn males are G6PD deficient with one third of them suffering jaundice within 48 hours of life and bilirubin levels remaining higher than 10 mg/dL. The most serious case occurred in a neonate with mild G6PD deficiency but with intense and prolonged bilirubin, suggesting that other factors are associated with hemolysis, as has previously been discussed.…”

Section: Neonatal Jaundice and Glucose-6-phosphate Dehydrogenasementioning

confidence: 77%

“…Other studies have also reported the frequency of G6PD deficiency ranging from 2 to 3% in the Brazilian population. (6)(7)(8)(9)(10)(11) Thus these data suggest that 6 million Brazilians have G6PD deficiency and that 1% of infants had episodes of jaundice to varying degrees associated to G6PD deficiency; 1.9 million Brazilians ran the risk of severe neonatal jaundice with a risk of kernicterus.…”

Section: Neonatal Jaundice and Glucose-6-phosphate Dehydrogenasementioning

confidence: 87%

“…Bligh and Dyer, (4) Rose-Gottlieb, (5) and Gerber (6) and an alternative technique, proposed by the authors, with the objective of comparing the efficiency of lipid extraction and to evaluate the fatty acid composition in total lipids from human plasma. …”

Section: Analysis Of Fatty Acids In Human Plasmamentioning

confidence: 99%

“…Accordingly, in this issue of the Journal of Hematology and Hemotherapy, a study by Morais et al (2) evaluated four classical methods of lipid extraction (the methods of Folch, Lees and Stanley, (3) Bligh and Dyer, (4) Rose-Gottlieb, (5) and Gerber (6) and an alternative technique, proposed by the authors, with the objective of comparing the efficiency of lipid extraction and to evaluate the fatty acid composition in total lipids from human plasma.…”

Section: Scientific Commentaries / Comentários Científicos Rev Bras Hmentioning

confidence: 99%

See 3 more Smart Citations

Icterícia neonatal e deficiência de glicose-6-fosfato desidrogenase

Leite¹

2010

Rev. Bras. Hematol. Hemoter.

View full text Add to dashboard Cite

Glucose -6-phosphate Analysis of fatty acids in human plasma Scientific commentaries / Comentários científicos Rev Bras Hematol Hemoter. 2010;32(6):430-433 In humans, omega-6 (n-6) and omega-3 (n-3) series fatty acids are important to maintain cell membranes, brain function and nerve impulse transmission.(1) Linoleic (LA, 18:2 n-6) and alpha-linolenic (LNA, 18:3 n-3) acids are strictly essential fatty acids, which must be obtained through the diet. The other n-6 and n-3 fatty acids can be synthesized from LA and LNA or be obtained through the diet.Of the n-6 and n-3 series fatty acids of nutritional value, arachidonic (AA, 20:4 n-6), eicosapentaenoic (EPA, 20:5 n-3) and docosahexaenoic (DHA, 22:6 n-3) acids are the most important.As in the human body, LA, an n-6 fatty acid, must be converted into AA, and LNA, an n-3 fatty acid, into EPA and DHA in order for them to exercise their functions, many kinetic studies are performed to measure these conversions from diets with different n-6/n-3 ratios.( 1) The first step in the process to assess the fatty acid composition of different foods and biological materials is to extract the lipids. Extraction methods are crucial to accurately measure fatty acid concentrations, as methods may degrade some fatty acids, especially polyunsaturated fatty acids and thus overestimate the true values.Accordingly, in this issue of the Journal of Hematology and Hemotherapy, a study by Morais et al. Bligh and Dyer, (4) Rose-Gottlieb, (5) and Gerber (6) and an alternative technique, proposed by the authors, with the objective of comparing the efficiency of lipid extraction and to evaluate the fatty acid composition in total lipids from human plasma.

show abstract

Section: Neonatal Jaundice and Glucose-6-phosphate Dehydrogenasementioning

confidence: 77%

Section: Neonatal Jaundice and Glucose-6-phosphate Dehydrogenasementioning

confidence: 87%

Section: Analysis Of Fatty Acids In Human Plasmamentioning

confidence: 99%

Section: Scientific Commentaries / Comentários Científicos Rev Bras Hmentioning

confidence: 99%

See 2 more Smart Citations

Icterícia neonatal e deficiência de glicose-6-fosfato desidrogenase

Leite¹

2010

Rev. Bras. Hematol. Hemoter.

View full text Add to dashboard Cite

show abstract

“…No Brasil, a avaliação da morbidade desta carência foi inicialmente realizada pelo estudo de Marques e Campos (1975), em hospitais de Belo Horizonte (MG), no qual registrou a deficiência em 7,8% mórbida, sendo os pacientes mais representados pela raça negra. Neste contexto, estima-se que no Brasil, aproximadamente cerca de 4% da população seja portadora ou doente desta deficiência (Iglessias et al, 2010).…”

Section: Introductionunclassified

Pharmaceutical care for patients with G6PD deficiency

Cordeiro

Correia

Guedes

2022

RSD

View full text Add to dashboard Cite

Historically, G6PD deficiency was reported for the first time in individuals who received doses of primaquine, the primary drug to be addressed in the study, to treat malaria, and triggered a symptomatic response with jaundice and a hematological field of erythroenzymopathies. In this sense, through an integrative review, the present research aimed to discuss the importance of pharmaceutical care and its relationship with the treatment of patients with G6DP enzyme deficiency. Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common enzyme deficiency prevalent in many malaria-endemic countries. In this sense, patients with G6PD deficiency are susceptible to hemolysis during oxidative stress, which can occur from exposure to certain drugs, including 8-aminoquinolines used to treat Plasmodium vivax malaria. In this way, pharmaceutical care would become a tool for monitoring patients and managing problems that may occur during pharmacotherapy. Guiding, educating and implementing quantitative mechanisms for diagnosing and providing adequate radical cure in heterozygous women, who remain at risk of hemolysis.

show abstract

Frequência da deficiência de glicose-6-fosfato desidrogenase (G-6-PD) e sua relação com a icterícia neonatal

Abstract: Avaliação: A RBHH publica os resumos e abstracts de teses da área apresentados em entidades que tenham programas de pós-graduação reconhecidos pelo MEC/Capes e considera a obtenção do título suficiente para sua publicação na forma como se propõe a seção.

Cited by 2 publications

References 0 publications

Icterícia neonatal e deficiência de glicose-6-fosfato desidrogenase

Icterícia neonatal e deficiência de glicose-6-fosfato desidrogenase

Pharmaceutical care for patients with G6PD deficiency

Contact Info

Product

Resources

About