Frequência de síndrome metabólica em crianças e adolescentes de escolas públicas de Divinópolis, Minas Gerais, Brasil, conforme três critérios diagnósticos internacionais

Abstract

Aims:To assess the frequency of metabolic syndrome in children and adolescents according to three international diagnostic criteria determining the level of agreement between these different criteria. Methods: Waist circumference, blood pressure, blood glucose, high-density lipoprotein cholesterol, and serum triglycerides were evaluated in students from public schools of different regions of Divinópolis, MG, Brazil. Children and adolescents aged between 10 and 17 years were selected. Criteria adapted from the World Health Organization (WHO), National Cholesterol Education Program -Adult Treatment Panel III (NCEP/ATPIII), and International Diabetes Federation (IDF) were used for the diagnosis of metabolic syndrome. The kappa coefficient was used to evaluate the level of agreement among the three criteria. Results: The study evaluated 202 students (86 boys and 116 girls). The frequency of metabolic syndrome was 1.16% for boys and none of the girls presented with metabolic syndrome, according to WHO criteria. According to the NCEP/ATPIII and IDF criteria, metabolic syndrome was not detected in the studied sample. Low blood levels of high-density lipoprotein cholesterol was the most frequent metabolic alteration in all teenagers according to the NCEP/ATPIII and IDF criteria, while body mass index was the most frequent one according to WHO criteria. The level of agreement for one altered parameter was poor when comparing WHO and NCEP/ATP/III, moderate when comparing WHO and IDF and high when comparing the NCEP/ATP/III and IDF criteria. Conclusions: Significant differences between the frequencies of individual metabolic syndrome parameters were found in the studied sample of children and adolescents, depending on the criteria used. According to WHO criteria, metabolic syndrome was found at a low frequency and only in boys, while the NCEP/ATPIII and IDF criteria did not diagnose metabolic syndrome. The present findings suggest the need to reach a consensus on the cut-off points for risk factors and a single diagnostic definition of metabolic syndrome in children and adolescents.KEY WORDS: metabolic syndrome X; child; adolescent. RESUMOObjetivos: Avaliar a frequência de síndrome metabólica em crianças e adolescentes de acordo com três critérios diagnósticos internacionais, determinando o grau de concordância entre esses diferentes critérios. Métodos: Circunferência da cintura, pressão arterial, glicemia, colesterol ligado à lipoproteína de alta densidade e triglicérides séricos foram avaliados em alunos de escolas públicas de diferentes regiões de Divinópolis, MG, Brasil. Foram selecionadas crianças e adolescentes entre 10 e 17 anos de idade. Critérios adaptados da Organização Mundial da Saúde (OMS), National Cholesterol Education Program, Adult Treatment Panel III (NCEP/ATP III) e da Federação Internacional de Diabetes (IDF) foram utilizados para o diagnóstico da síndrome metabólica. O coeficiente kappa foi utilizado para avaliar o grau de concordância entre os três critérios. Resultados: O estudo avaliou 202 ...

Prevalence of metabolic syndrome in Brazilian children using three different sets of international criteria

“…The association of MetS with overweight and obesity is well established even in children and adolescents (1,7,8). This association is stronger when considering not only the excess of body fat, but when related to central obesity (9).…”

“…Additionally, there is no agreement on the cut-off points to be used for MetS components. Many studies have compared different MetS diagnostic criteria in different populations, but there is no consensus about which one shows a higher accuracy in children (7,15,17,(19)(20)(21). As children with MetS have an increased risk of developing cardiovascular disease during their adulthood (22,23), the diagnosis of MetS during childhood and an early intervention might probably benefit their health status in the future.…”

Frequência da síndrome metabólica em pacientes esquizofrênicos

“…A Síndrome Metabólica (SM) é vista como uma epidemia mundial e os números de morbidade, mortalidade cardiovascular e custos socioeconômico aos serviços públicos de saúde são alarmantes é vista como uma epidemia mundial (Granjeiro et al, 2016). É caracterizada por um conjunto de fatores que aumentam o risco de sofrer doenças cardiovasculares, também está relacionada à obesidade central e à resistência à insulina.…”

“…* Homens, ** Mulher. Fonte:Granjeiro (2016). apresentadas por mediana e intervalo interquartil (percentil 25 e percentil 75).…”

Frequência de síndrome metabólica em estudantes de uma universidade pública brasileira

“…Dentre as possíveis causas do surgimento dos seus componentes estão os hábitos alimentares inadequados (Oliveira et al, 2009), maior probabilidade de desenvolver SM pessoas que sofrem estresse no trabalho, os obesos, sedentários com padrões dietéticos hipercalóricos e fatores genético desfavoráveis (Freitas et al, 2012), assim como pessoas que possuem resistência à insulina e intolerância à glicose (Morrell et al, 2012), assim como em pacientes esquizofrênico com influência de polimorfismo nos genes ANKK1, DRD2 e DRD3 (Pinto et al, 2018). Esses hábitos de vida vêm contribuindo com a prevalência de SM desde a infância (Granjeiro et al, 2016;Gonçalves et al, 2021).…”