Frequencies and ethnic distribution of ABO and RhD blood groups in the Volta region of Ghana, towards effective blood bank services

Doku, George N.; Agbozo, William Kweku; Annor, Rabia Asiba; Mawudzro, Priscilla E; Agbeli, Elizabeth E

doi:10.4314/ahs.v22i1.74

Cited by 7 publications

(7 citation statements)

References 12 publications

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“…However, only age and season showed significant associations with the ABO blood group (p≤0.001, and p=0.008, respectively). This corroborates similar patterns reported in other parts of Ghana [14,15]. In the rainy season, blood type B was the second most frequent phenotype after blood type O, whereas in the dry season, blood type A was second after the O phenotype.…”

Section: Discussionsupporting

confidence: 91%

“…Although not significant, the small number of Rh-negative patients presented in each sociodemographic stratification of gender, age, and season and the overall low frequency (6.9%) suggest a scarcity of the Rh-negative phenotype in the general population. This finding corroborates similar studies conducted in the Volta [14] and Greater Accra Regions of Ghana [15]. This may culminate in shortages of Rh-negative blood types and could lead to mortalities in patients in need of such blood types.…”

Section: Discussionsupporting

confidence: 91%

“…Blood transfusion centers in Ghana must maintain a functional inventory for the different seasons to help them stock the required blood group phenotypes to prevent blood shortages and avoidable deaths. However, the few studies [14,15] that reported the distribution of different blood group phenotypes in Ghana only highlighted the ethnic variations of the ABO and Rh blood group phenotypes, while they failed to report the association between these phenotypes and season. Therefore, this study determined the patterns of blood transfusion and the effect of season on ABO/Rh blood group phenotypes among hospitalized patients.…”

Section: Introductionmentioning

confidence: 99%

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Effect of Season on Blood Transfusion Patterns: A Retrospective Study

Osei-Boakye,

Agyepong,

Nkansah

et al. 2023

SciMed. J.

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Background: Different seasons present varied environmental factors that influence the occurrence of transfusion-driven diseases. Therefore, this study determined the patterns of blood transfusion among hospitalized patients and the effect of season on ABO/Rh phenotypes. Methods: A single-center retrospective cross-sectional study was conducted on 5089 hospitalized patients that were transfused with blood at Sunyani Municipal Hospital. Archived blood transfusion records were retrieved and analyzed using GraphPad Prism, and SPSS. The association, effect size, and yearly trends of transfusion patterns were determined. Results: The majority of the participants were females (63.0% [3208]), 36-49 years old (20.4% [1039]), O phenotype (48.1% [2447]), Rh-positive (93.1% [4737]), and transfused in the rainy season (61.0% [3103]). Patients’ ABO was weakly associated with age (r = 0.07, p≤0.001) and season (r = 0.05, p = 0.008). Eighty percent (4053/5089) of the transfusions were ABO group-specific, and 28.3% (1146/4053) of this occurred at the emergency ward. The source of transfusion request was weakly associated with season (r = 0.1, p≤0.001) and type of transfusion (r = 0.1, p = 0.002). The rainy season (slope: 142.9, p≤0.001) and ABO-specific transfusions (slope: 219.5, p≤0.001) showed consistent increasing trends over the years. Conclusion: Blood transfusion was frequent among females, adults, Rh-positive and O phenotypes, and in the rainy season. Age and season were significantly associated with ABO, but not Rh. A transfusion request was associated with the season and type of transfusion, with the majority of transfusions occurring in the rainy season and emergency ward. There was an increasing yearly trend in blood transfusions. Doi: 10.28991/SciMedJ-2023-05-02-03 Full Text: PDF

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Season on Blood Transfusion Patterns: A Retrospective Study

Osei-Boakye,

Agyepong,

Nkansah

et al. 2023

SciMed. J.

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“…Concerning association of ABO blood groups and ethnic groups, a study which was done in Cameroon25 and another one in Ghana26 both reported association between ABO blood groups and ethnic groups. We also observed an increased prevalence of blood group A among donors from Manyara region as compared with other regions (Kilimanjaro, Arusha and Tanga) although the difference did not reach research statistical difference.…”

Section: Discussionmentioning

confidence: 99%

Frequency and distribution of ABO and Rh blood group systems among blood donors at the Northern Zone Blood Transfusion Center in Kilimanjaro, Tanzania: a retrospective cross-sectional study

et al. 2023

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ObjectivesABO and Rh blood group systems are the major factors affecting the blood transfusion safety. The frequency and distribution of these blood group systems vary worldwide. We aimed to determine the frequency and distribution of ABO and Rh blood group systems among first-time blood donors at the Northern Zone Blood Transfusion Center in Kilimanjaro, Tanzania.DesignCross-sectional descriptive population-based study.SettingData on ABO and Rh blood group systems were obtained and analysed from the Northern Zone Blood Transfusion Center among first-time blood donors.ParticipantsThere were 65 535 first-time blood donors aged 15–55 years who donated at the Northern Zone Blood Transfusion Center from January 2017 to December 2019.Outcome measuresThe percentage of ABO and Rh blood group systems among different categories of blood donors was calculated.ResultsRetrospective data from Blood Establishment Computer System of 65 535 first-time blood donors were analysed in the present study. The mean age of the blood donors was 30.6±11.2 years (range: 15–55 years). The vast majority of the blood donors 84.2% (n=55 210) were men. Also, the majority 69.6% (n=45 595) were aged ≥35 years. Blood group O was the most common blood group which was found in over half 52.4% (n=34 333) of the blood donors and majority 95.3% (n=62 461) of the donors were Rh positive. Moreover, the majority 78.3% (n=51 336) were voluntary donors and the remaining 21.7% (n=14 199) were replacement donors.ConclusionMajority of the donors had blood group O and also the vast majority of the donors were Rh positive. Considering the large size of our study population, this has provided a more comprehensive information regarding the frequency and patterns of ABO and Rh blood group systems in Tanzania. The observed association of blood group A with one of the regions from which donors were coming from, is intriguing and further studies may confirm possible related genetic evolution.

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“…Oral et al, did not report a significant relationship between the type of blood group with the survival rate of HCC after hepatectomy [ 27 ]. The distribution of blood groups in different countries is different [ 28 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of ABO blood group on postoperative overall survival and recurrence-free survival rate in patients with hepatocellular carcinoma after hepatectomy: a multi-center retrospective cohort study

Bahardoust,

Dehkharghani,

Ebrahimi

et al. 2023

BMC Surg

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Background Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. The survival rate after hepatectomy as the first line of treatment for HCC depends on various factors. This study evaluated the association of the ABO blood group and Rh with overall survival (OS) and Recurrence-free survival (RFS) rate after hepatectomy. Methods This multicenter retrospective cohort study reviewed the medical files of 639 HCC patients who underwent hepatectomy from 2010 to 2022 in three medical centers affiliated with the Iran University of Medical Sciences. Patient data, including demographic, clinical, tumor characteristics, and post-surgery outcomes, were collected by referring to the patient’s medical profiles. The Cox proportional hazard investigated the relationship between ABO blood group type and OS and RFS rate after hepatectomy. Results The five-year OS and RFS rates were 25.4% and 18.7%, respectively. The five-year OS (Lok rank:40.89, P:0.001) and RFS rate in patients with blood type A were significantly lower than in non-A patients. (Lok rank:10.8, P:0.001) The multivariate Cox analysis showed that blood type A, age < 45 years, tumor size > 5 cm, Poor tumor differentiation, presence of metastasis, The number of involved lymph nodes ≤ 2, and serum Alpha-Fetoprotein)AFP( level ≥ 400 were significantly related to the decreased survival rate of HCC patients after hepatectomy (P < 0.05) There was no significant association between Rh with OS and RFS (P > 0.05). Conclusion Blood group type A, compared to non-A, can be associated with decreased OS and RFS rates in patients with HCC after hepatectomy.

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Frequencies and ethnic distribution of ABO and RhD blood groups in the Volta region of Ghana, towards effective blood bank services

Cited by 7 publications

References 12 publications

Effect of Season on Blood Transfusion Patterns: A Retrospective Study

Effect of Season on Blood Transfusion Patterns: A Retrospective Study

Frequency and distribution of ABO and Rh blood group systems among blood donors at the Northern Zone Blood Transfusion Center in Kilimanjaro, Tanzania: a retrospective cross-sectional study

Effect of ABO blood group on postoperative overall survival and recurrence-free survival rate in patients with hepatocellular carcinoma after hepatectomy: a multi-center retrospective cohort study

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