Frequency and clinico-topographic distribution patterns of pruritic papular eruption in HIV patients in a Nigerian Tertiary Hospital

Ekpe, Obioma; Forae, Gerald Dafe; Okwara, Benson Uchechukwu

doi:10.7241/ourd.20194.3

Cited by 3 publications

(3 citation statements)

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“…Pruritus, which is usually caused by immune dysregulation [7], was seen in 5.8% of our cases. Even the prevalence of pruritus in our study was lower compared to other studies, which estimate it at approx.…”

Section: Discussionmentioning

confidence: 63%

Mucocutaneous disorders in HIV/AIDS at a tertiary care hospital in Nepal: An observational study

Rajput¹,

Das²,

Paudel³

et al. 2021

Our Dermatol Online

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Background: Mucocutaneous manifestations in HIV infections are common. However, they have not, so far, been studied in Nepal. The aim of this study was, therefore, to describe mucocutaneous manifestations in Nepalese HIV patients. Materials and Methods: The following is a hospital-based, descriptive, cross-sectional study conducted in the Department of Dermatology and Venereology and Antiretroviral Treatment (ART) Center of Tribhuvan University Teaching Hospital (TUTH) from May 2017, through October 2018. Patients aged 16 years and above diagnosed with HIV were included in the study, for whom history and clinical examinations were performed. The study variables were age, sex, a clinical diagnosis of dermatological problems, clinical stages of HIV/AIDS, as per the World Health Organization (WHO) classification criteria, and the CD4 count. Results: A total of 52 patients were included in the study. The mean age upon presentation was 38.77 ± 10.9 years. The mean CD4 count was 464.27 ± 255.13. Females were more affected than males (female:male = 1.4:1). Mucocutaneous manifestations were the following: fungal infections (10; 19.3%), viral infections (6; 11.6%), parasitic infestations (3; 5.8%), bacterial infections (4; 7.7%), sexually transmitted infections (2; 3.8%), seborrheic dermatitis (3; 5.8%), idiopathic pruritus (3; 5.8%), recurrent oral ulcers (3; 5.8%), urticaria (3; 5.8%), pruritic papular eruptions (2; 3.8%), eczemas (2; 3.8%), acne (2; 3.8%), angular cheilitis (2; 3.8%), xerosis cutis (2; 3.8%), and others (5; 9.6%). Conclusions: The study showed that fungal infections are common in HIV patients, followed by viral infections and parasitic infestations. Seborrheic dermatitis, idiopathic pruritus, recurrent oral ulcers, and urticaria were found to be common inflammatory skin diseases in HIV.

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Section: Discussionmentioning

confidence: 63%

Mucocutaneous disorders in HIV/AIDS at a tertiary care hospital in Nepal: An observational study

Rajput¹,

Das²,

Paudel³

et al. 2021

Our Dermatol Online

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“…Pigmentasi pascainflamasi, nodul dan jaringan parut seperti prurigo dapat berkembang sekunder akibat eksoriasi ekstensif karena gatal yang parah. Papular pruritic eruption menyebabkan kondisi gatal yang hebat dan menahun sehingga dapat mengganggu kualitas hidup penderitanya (Ekpe et al, 2020).…”

Section: Pembahasanunclassified

Karakteristik Penyakit Kulit dan Kelamin pada Penderita Infeksi Human Immunodeficiency Virus di Rumah Sakit Umum Daerah Buleleng

Supradnyan,

Wijaya,

Wibawa

2024

JKH

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Latar Belekang: Berbagai penyakit kulit dan kelamin telah dihubungkan dengan infeksi HIV. Penyakit tersebut dapat secara spesifik berhubungan dengan HIV, namun bisa juga merupakan penyakit umum namun dengan manifestasi yang lebih parah dan lebih sulit diobati. Tujuan: untuk mengetahui karakteristik penyakit kulit dan kelamin pada pasien dengan infeksi HIV di Rumah Sakit Umum Daerah Buleleng. Metode: Penelitian ini menggunakan pendekatan studi potong lintang yang dilakukan pada periode bulan Mei 2023 hingga Juli 2023. Diagnosis infeksi HIV dibuktikan dengan pemeriksaan laboratorium, sementara itu diagnosis penyakit kulit dan kelamin ditegakkan secara klinis oleh dokter spesialis kulit dan kelamin, dan apabila diperlukan dilakukan pemeriksaan penunjang. Hasil: Terdapat 28 pasien HIV dengan keluhan penyakit kulit dan kelamin. Jumlah pasien laki-laki dibanding perempuan adalah 2,1:1 dengan dominasi pada kelompok umur 31-40 tahun. Sebagian besar dari pasien berada pada stadium 4 dan rute penularan terbanyak adalah karena seks bebas dan homoseksual. Terdapat 49 diagnosis di bidang kulit dan kelamin dari 28 pasien yang diperiksa. Karakteristik penyakit kulit dan kelamin pada pasien adalah 57,1 % diagnosis penyakit infeksi, sisanya adalah penyakit non infeksi. Kesimpulan: Penyakit infeksi diantaranya adalah infeksi bakteri (sifilis, ektima, granuloma inguinale, bartholinitis dan impetigo krustosa), infeksi virus (herpes zoster, kondiloma akuminata, moluskum kontagiosum dan herpes labialis) dan infeksi jamur (kandidiasis oroesofageal, kandidiasis oral dan angular cheilitis). Sementara itu, untuk kasus non infeksi terdiri dari dermatitis seboroik, papular pruritic eruption dan erupsi obat.

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“…L'urticaire constitue un motif de consultation fréquent en dermatologie et peut affecter jusqu'à 20% de la population générale [2]. Le diagnostic positif de l'urticaire est clinique [3,4]. Il s'agit d'une affection dont les causes sont multiples et variées [5][6][7][8].…”

Section: Introductionunclassified

Untitled

2021

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The aim of this study was to document the epidemiological, clinical, therapeutic and progressive profile of chronic urticaria in dermatology in Lomé (Togo). Patients and Method: We carried out a prospective study in the three public dermatology departments of Lomé from November 2017 to April 2019. All patients with chronic urticaria diagnostic were included. Results: In total, 129 (1.1%) of the 11,355 patients seen during the study period had chronic urticaria. The mean age of the patients was 34.5 ± 13 years and the sex ratio (M / F) was 0.49. A history of personal (65.1%) or familial (47.6%) atopy was found. Typical fleeting edematous papular lesions were present in 100% of patients and angioedema in 52 (40.3%) patients. Treatment was based on antihistamines antis H1 (100% of patients); mainly second generation (86% of patients). Remission was noted in 69.9% of patients. Conclusion: Chronic urticaria is a rare pathology in dermatological consultation in Lomé. The superficial forms are the most observed.

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Frequency and clinico-topographic distribution patterns of pruritic papular eruption in HIV patients in a Nigerian Tertiary Hospital

Abstract: Background: Pruritic papular eruption of HIV (PPE-HIV) has been well described in some sub-Saharan Africa countries and elsewhere, with varying geographical prevalence. Aims: To determine the frequency and the clinico-topographic distribution of these lesions as seen in the

Cited by 3 publications

References 18 publications

Mucocutaneous disorders in HIV/AIDS at a tertiary care hospital in Nepal: An observational study

Mucocutaneous disorders in HIV/AIDS at a tertiary care hospital in Nepal: An observational study

Karakteristik Penyakit Kulit dan Kelamin pada Penderita Infeksi Human Immunodeficiency Virus di Rumah Sakit Umum Daerah Buleleng

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