Frequency and outcomes of benign breast biopsies in trans women: A nationwide cohort study

Blok, Christel J.M. de; Dijkman, Benthe A M; Wiepjes, Chantal M.; Konings, Inge R.; Dreijerink, Koen M.A.; Barbé, Ellis; Heijer, Martin den

doi:10.1016/j.breast.2021.03.007

Cited by 15 publications

(6 citation statements)

References 24 publications

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“…While the exact risk to this population is unclear, the repeated cases do highlight that malignancy is a differential that must be considered and excluded. However, over testing to exclude malignancy is not required rather the same index of suspicion should be applied to transwomen as compared with cis -women as their ratio of benign to malignant lesions is comparable to that of cis -women [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

Fibroadenoma in a transgender woman

Beatty

Tam

2023

Journal of Surgical Case Reports

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A breast fibroadenoma is a common benign condition that is typically seen in younger women. Rarely has it been described in men and often because of prescribed medications, but for transgender women, this occurrence is even rarer. Endocrine therapy plays a key role in the transition of a transwoman from male to female of which oestrogen is the most common form. The use of cross-sex hormones such as oestrogen is becoming increasingly more utilized in this transition helping in feminization but also secondary breast development. However, this does result in the development of other breast pathologies that were almost never seen in their cis-male counterparts. Herein, we present the case of a 27-year-old transwoman who presented with a palpable breast lump after being on oral oestrogen therapy for 6 years. She proceeded to an excisional biopsy, which confirmed the lesion to be a benign fibroadenoma.

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Section: Discussionmentioning

confidence: 99%

Fibroadenoma in a transgender woman

Beatty

Tam

2023

Journal of Surgical Case Reports

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“…However, because our diagnosis was mainly clinical, some cases of lactational breast abscesses may have gone undetected. In contrast, De Block et al 18 study whose denominator was exact, followed up on 1193 breastfeeding women by telephone conversations at 6 months. Mastitis can appear at any point during lactation according to studies, but it typically happens during the first six weeks.…”

Section: Discussionmentioning

confidence: 99%

Frequency of Breast Abscess among Lactating Women Presenting to Ambulatory Care of Tertiary care Hospital

Ahmad¹,

Amin²,

Alam³

2023

PJMHS

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Background: The excruciating build-up of pus in breast tissue is known as a breast abscess. This condition is more common in lactating women and is caused by bacterial infection at the nipple zone, which is primarily brought on by biting the child while breastfeeding, poor sanitation, blockage of the milk ducts, and the development of lumps that may be cancerous. Mastitis to abscess development is at different levels of severity for breast abscesses. Breast abscesses can be central or perieolar in location. Acute cases are readily treatable, but surgical intervention is required for chronic cases. Aim: To determine the frequency of breast abscess among lactating women presenting to ambulatory care of tertiary care hospital of Peshawar. Study design: Cross-sectional observational study. Place and duration of study: Department of General Surgery, Hayatabad Medical Complex Peshawar from 1st March 2021 to 1st September 2021. Methodology: Three hundred and thirty four patients of ae groups 15–45 years old, lactating mothers up to 40 days after childbirth, and all women presenting with mastalgia (more than 3 on visual analogue scale) were included. Patients with an alternate infection site identified through clinical examination, those with diabetes (FBS >120mg/dl), those with other immunosuppressive conditions like HIV, and those with a history of steroid use within the previous month were excluded. Results: There were 49(14.7%) cases belong to age group of 19-30 years, while 31(9.3%) belongs to >30 years age (p 0.049). Thirty six (10.8%) of abscess was noted in those who had parity of 1-2 while 44(13.2%) had parity 3-4. The mean BMI of the study sample was 26.6+3.5kg/m2 amongst whom 29(8.7%) frequency of breast abscess was observed in 18.5-24.9 kg/m2, 36(10.8%) had BMI of 25-29.9 kg/m2 and 15(4.5%) had >30kg/m2. The mean postpartum day was 12.1±4.1 day. Fifty four (16.2%) abscess was noted in 6-12 postpartum day, while 26(7.8%) was noted in >12-19 postpartum day. Conclusion: Breast abscess was fairly common (24%) in postpartum women and significantly associated with age of the patient (>30 years). Keywords: Breast abscess, Parity, Lactating women, Post-partum, Body mass index

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“…It is expected that the risk of BC in this group is higher than FBC, as these patients receive female hormones; however, this increase does not reach the risk of BC in cis women (54). There is an estimated 46-fold increase in risk of BC for trans women compared to cis men, but their risk is still lower than that of cis women, most likely explained by lower hormone levels (albeit prolonged hormone exposure) (55).…”

Section: Bc In Trans Womenmentioning

confidence: 95%

An introduction to male breast cancer for urologists: epidemiology, diagnosis, principles of treatment, and special situations

et al. 2022

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Breast cancer (BC) is mainly considered a disease in women, but male BC (MaBC) accounts for approximately 1.0% of BC diagnoses and 0.5% of malignant neoplasms in the western population. The stigmatization of MaBC, the fact that men are less likely to undergo regular health screenings, and the limited knowledge of health professionals about MaBC contribute to men being diagnosed at more advanced stages. The aim of this article is to increase the visibility of MaBC among urologists, who have more contact with male patients. This review highlights key points about the disease, the risk factors associated with MaBC, and the options for treatment. Obesity and increased population longevity are among the important risk factors for MaBC, but published studies have identified family history as extremely relevant in these patients and associated with a high penetrance at any age. There is currently no screening for MaBC in the general population, but the possibility of screening in men at high risk for developing BC can be considered. The treatment of MaBC is multidisciplinary, and, because of its rarity, there are no robust clinical studies evaluating the role of systemic therapies in the management of both localized and metastatic disease. Therefore, in current clinical practice, treatment strategies for men with breast cancer are extrapolated from information arising from studies in female patients.

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Frequency and outcomes of benign breast biopsies in trans women: A nationwide cohort study

Cited by 15 publications

References 24 publications

Fibroadenoma in a transgender woman

Fibroadenoma in a transgender woman

Frequency of Breast Abscess among Lactating Women Presenting to Ambulatory Care of Tertiary care Hospital

An introduction to male breast cancer for urologists: epidemiology, diagnosis, principles of treatment, and special situations

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