Frequency and predictors of suboptimal glycemic control in an African diabetic population

Kibirige, Davis; Akabwai, George Patrick; Kampiire, Leaticia; Kiggundu, Daniel Ssekikubo; Lumu, William

doi:10.2147/ijgm.s124548

Cited by 34 publications

(36 citation statements)

References 17 publications

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“…These results highlight the need to work more on optimum management of diabetes, as maintaining good glycemic control is main therapeutic goal for all patients with diabetes. The overall rates of poor glycemic control found in our study was higher than previous estimates from studies in Costa Rica (37%) [ 23 ], Zambia (61.3%) [ 24 ], and Kenya (60.5%) [ 25 ] but lower than that found in Uganda (73.5%) [ 13 ] and Brazil (76%) [ 26 ], which also included type 1 and 2 diabetic patients. This might be due to differences in populations studded, sample size, methods of data collection or method of assay for defining glycaemic control.…”

Section: Main Textscontrasting

confidence: 90%

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Factors associated with glycemic control among diabetic adult out-patients in Northeast Ethiopia

et al. 2018

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ObjectiveThe aim of this study was to determine the status of glycemic control and identify factors associated with poor glycemic control among diabetic out-patients.ResultsA hospital based cross-sectional study was conducted among randomly selected 384 (126 type 1 and 258 type 2) diabetic adults attending a hospital in Northeast Ethiopia from January 1 to April 30, 2017. Of the total participants, 70.8% had poor status of glycemic control (defined as mean fasting blood glucose level above 130 mg/dl). In the multivariate analysis, rural residence (AOR = 2.61, 95% CI 1.37–4.96), low educational level (AOR = 7.10, 95% CI 2.94–17.17) and longer duration of diabetes (AOR = 2.20, 95% CI 1.18–4.08) were significantly associated with increased odds of poor glycemic control. Moreover, merchants (AOR = 3.39, 95% CI 1.16–9.96) were significantly more likely to have poor glycemic control compared to government employee. Diabetic patients receiving oral anti-diabetics (AOR = 5.12, 95% CI 2.10–12.52) or insulin (AOR = 3.26, 95% CI 1.26–8.48) were more likely to be poorly controlled. These results highlight the needed for appropriate management of patients focusing on associated factors identified for poor glycemic control to maintain good glycemic control and improve adverse outcomes of the disease in this study setting.

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Section: Main Textscontrasting

confidence: 90%

“…Despite this evidence, a high proportion of patients with diabetes remains poorly controlled. This is particularly the case in most countries of SSA where the majority of patients in clinical care do not reach the optimal glucose targets [ 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Factors associated with glycemic control among diabetic adult out-patients in Northeast Ethiopia

et al. 2018

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“…Pada penelitian penggunaan kombinasi dua obat yaitu metformin dan sulfonilurea memproleh angka ketercapaian target terapi paling baik sebesar 31% penggunaan kombinasi dua obat memperlihatkan hasil yang efektif karena mekanisme aksi kerja dua obat yang berbeda dan minimal resiko adverse effect 12,13 . Rendahnya kontrol glikemik juga ditemukan pada pasien dengan pemberian monoterapi 14 Diabetes merupakan penyakit kronis yang memerlukan terapi berkelanjutan, patient self care dan edukasi untuk mencegah terjadinya komplikasi. Peran farmasis adalah membantu pasien untuk lebih mengenal penyakit dan terapinya dengan cara memberikan edukasi yang tepat terkait penyakit diabetes, studi menunjukan bahwa intervensi farmasis dapat mempengaruhi outcome klinik dan kepuasan terapi pasien, yang merupakan indikator krusial kualitas pelayanan kesehatan dan merupakan kunci kepatuhan pasien dengan melakukan kegiatan misalnya support of self blood glucose monitoring (SMBG), monitoring kepatuhan pasien, dan mengidentifikasi masalah terkait terapi atau drug related problem (DRP) 15,16 .…”

Section: Tabel I Karakteristik Pasienunclassified

Hubungan Tingkat Pengetahuan terhadap Outcome Klinik Pasien Diabetes Melitus Tipe 2

Larasati

Andayani

Kristina

2019

J. Manaj. dan Pelayanan Farm.

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Diabetes is a chronic disease that requires good therapeutic management and self care to achieve optimal glycemic target. The important barrier to achieve good glycemic control is a lack of knowledge about optimal glycemic targets. The purpose of this study was to determine the relationship of the level of knowledge to clinical outcome of type 2 diabetes mellitus in Yogyakarta and Bantul primary health care. This was an observational study with a cross sectional design. The sampling technique was done by accidental sampling for patients visiting the primary health care from October to December 2018 that involved 200 type 2 diabetes mellitus patients who were included in the inclusion criteria. The level of knowledge was measured by the Diabetes Knowledge Questionnaire (DKQ)-24 which had 24 questions and the clinical outcome was obtained from laboratory measurement data as well as from medical record data when the patient was in routine control. Sociodemographic data were analyzed descriptively. The relationship between the level of knowledge and clinical outcomes was analyzed using chi square. The results showed that the knowledge level score had an average value of 12. The most incorrect answer was in etiology and diabetes self care, which is eating too much sugar and sweet foods is the cause of diabetes (97%), exercise regularly increasing the need of hormone insulin or diabetes medication (82%), the insulin reaction is caused by too much food (84%) and diabetics should clean the wound with betadine and alcohol (88%). There were 106 (53%) patients who achieved good glycemic control. Chi square test showed no relationship between the level of knowledge of clinical outcomes (p = 0.328). The result of this study may become a material and education content evaluation in diabetic patients.

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“…In press 2017. 17 Abbreviations: IQR, interquartile range; HT, hypertension; DM, diabetes mellitus; Met, metformin; SU, sulfonylurea; BMI, body mass index; HbA1c, glycated hemoglobin; LDLC, low-density lipoprotein cholesterol; HDLC, high-density lipoprotein cholesterol; TC, total cholesterol; TGL, triglyceride; TZD, thiazolidinedione; SBP, systolic blood pressure; DBP, diastolic blood pressure. …”

Section: Figurementioning

confidence: 99%

Statin therapy reduces the likelihood of suboptimal blood pressure control among Ugandan adult diabetic patients

Lumu

Kampiire

Akabwai

et al. 2017

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BackgroundHypertension is one of the recognized risk factors of cardiovascular diseases in adult diabetic patients. High prevalence of suboptimal blood pressure (BP) control has been well documented in the majority of studies assessing BP control in diabetic patients in sub-Saharan Africa. In Uganda, there is a dearth of similar studies. This study evaluated the prevalence and correlates of suboptimal BP control in an adult diabetic population in Uganda.Patients and methodsThis was a cross-sectional study that enrolled 425 eligible ambulatory adult diabetic patients attending three urban diabetic outpatient clinics over 11 months. Data about their sociodemographic characteristics and clinical history were collected using pre-tested questionnaires. Suboptimal BP control was defined according to the 2015 American Diabetes Association standards of diabetes care guideline as BP levels ≥140/90 mmHg.ResultsThe mean age of the study participants was 52.2±14.4 years, with the majority being females (283, 66.9%). Suboptimal BP control was documented in 192 (45.3%) study participants and was independently associated with the study site (private hospitals; odds ratio 2.01, 95% confidence interval 1.18–3.43, P=0.01) and use of statin therapy (odds ratio 0.5, 95% confidence interval 0.26–0.96, P=0.037).ConclusionSuboptimal BP control was highly prevalent in this study population. Strategies to improve optimal BP control, especially in the private hospitals, and the use of statin therapy should be encouraged in adult diabetic patients.

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Frequency and predictors of suboptimal glycemic control in an African diabetic population

Cited by 34 publications

References 17 publications

Factors associated with glycemic control among diabetic adult out-patients in Northeast Ethiopia

Factors associated with glycemic control among diabetic adult out-patients in Northeast Ethiopia

Hubungan Tingkat Pengetahuan terhadap Outcome Klinik Pasien Diabetes Melitus Tipe 2

Statin therapy reduces the likelihood of suboptimal blood pressure control among Ugandan adult diabetic patients

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