Frequency and prognosis of acute pancreatitis associated with acute hepatitis E: A systematic review

An Unexpected Cause of Pancreatitis

“…Eighteen percent developed severe acute pancreatitis, with mortality reported in 2 patients. 3 Autochthonous HEV infection, like in our case, is generally reported in the older male population. 1 It is important to be vigilant of this emerging infection in the developed world, and to include in a differential diagnosis even with no overt risk factors or travel history.…”

Acute liver failure caused by hepatitis E virus genotype 3 and 4: A systematic review and pooled analysis

“…HEV infection can cause asymptomatic, anicteric or icteric acute hepatitis as well as fulminant hepatitis, or acute‐on‐chronic liver failure. Moreover, this infection may not be readily recognized at times, as it may masquerade as DILI, AIH or with myriad of extrahepatic manifestations, such as neurological symptoms, acute pancreatitis, chronic renal disease and cryoglobulinaemic disease …”

“…Moreover, this infection may not be readily recognized at times, as it may masquerade as DILI, 50 AIH 51 or with myriad of extrahepatic manifestations, such as neurological symptoms, acute pancreatitis, chronic renal disease and cryoglobulinaemic disease. 11,13,[52][53][54] In highly endemic areas, a small proportion of patients with acute HEV may develop ALF (0.5%-4%). 1 In areas with lower endemicity, occurrence of ALF caused by genotype 3 and 4 has not been previously systematically evaluated, and there is a general belief that genotype 3 and 4 carry a benign course usually.…”

The utility of optical coherence tomography for diagnosis of basal cell carcinoma: a quantitative review

“…Given the lack of validated tools for quality assessment of noncomparative studies, we employed a previously used, modified NOS for evaluation of case series and case reports included in the review . In this adapted version, items associated with comparability and adjustment were removed, while those focusing on patient selection, case representativeness and reporting of exposure and outcome were retained.…”