Frequency and Relevance of Thyroid Dysfunction in Patients with Chronic Heart Failure: A Cross Sectional Study at Yaoundé Central Hospital, Cameroon

Honoré, Kemnang Yemele; Moor, Vicky Jocélyne Ama; Kuaté, Liliane Mfeukeu; Etoa, Martine; Daryl, Tcheutchoua Nzokou; Agoons, Batakeh B.; Samba, Esther Mbono; Amazia, Falmata; Gaelle, Nangue Tiogoung; Arnaud, Ossongo; E, Manuela; MacBrain, Elage Epie; Nkeck, Jan René

doi:10.26502/acbr.50170154

Cited by 2 publications

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“…Thyroid disorder patients were grouped into four categories. Most of our patients had subclinical hypothyroidism, followed by overt hypothyroidism and overt hyperthyroidism, with similar findings reported by Mfeukeu-Kuate et al 8 Another study from Cameroon conducted by Yemele Honoré, Kemnang et al revealed that approximately two-thirds of their study participants had euthyroid, while 25 (39.7%) were dysthyroid (30).Bernad et Biondi et al conducted a study in Italy and suggested that the SHypo with TSH >10 mU/l is a significant risk factor for HF in older patients. A meta-analysis of six prospective cohort studies involving a total of 2068 patients with SHypo recently validated these findings.…”

Section: Discussionsupporting

confidence: 92%

“…About 7–8% of middle-aged hyperthyroid patients develop atrial fibrillation or flutter; this risk rises to 10–20% in elderly patients and up to 20–35% in those over 65. 8 Lippi G, Sanchis-Gomar F et al studied the prevalence and types of thyroid dysfunction in patients with chronic HF in Africa, as well as the factors that contribute to it. They reported that hypertension (52.4%) and valvular heart disease (14.3%) were the most common causes of HF.…”

Section: Discussionmentioning

confidence: 99%

“… 7 Low T3 syndrome (LT3S) affects 20 to 30% of people with chronic heart failure and is characterized by a decrease in Free triiodothyronine (FT3) with normal levels of free thyroxine (FT4) and thyroid stimulating hormone (TSH). 8 Other studies show that fT3 supplementation increases life expectancy in these patients. 9 Given the importance of thyroid abnormalities in patients with chronic HF and their impact on prognosis, thyroid function should be checked regularly in these patients, according to the American Heart Association.…”

Section: Introductionmentioning

confidence: 93%

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Prevalence of Thyroid Dysfunction Among Patients with Heart Failure at a Tertiary Hospital in Mogadishu, Somalia

Mohamud¹,

İbrahim²,

Ahmed³

et al. 2022

IJGM

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Introduction Thyroid disease is an independent predictor of heart failure in patients. This study aimed to investigate the prevalence of thyroid dysfunction among patients with heart failure in Mogadishu, Somalia. Methods From January 2019 to January 2021, a total of 250 patients diagnosed with heart failure admitted to the cardiology outpatient and emergency departments were evaluated retrospectively. The demographic characteristics, the cause of heart failure, and the kind of heart failure were recorded. Patients were categorized into subclinical hypothyroidism, hypothyroidism, low T3 syndrome, subclinical hyperthyroidism, and hyperthyroidism. Results A total of 250 heart failure patients. The prevalence of thyroid dysfunction among heart failure patients was 35.6%. The mean age of the patients was 59.8±14 years. Males outnumbered females by 159 (63.2%). The prevalence of thyroid dysfunction was 35.6%. Out of the 250 patients that were examined, most of the patients 30(33.3%) had subclinical hypothyroidism. 23 (25.6%) had overt hypothyroidism, 15 (16.7%) had overt hyperthyroidism, 20 (22.2%) had low T3 syndrome, and two cases had subclinical hyperthyroidism. Regarding the gender status of the thyroid dysfunction, 43(48.3%) were male, and 46(51.7%) were female. Regarding heart failure types among thyroid dysfunction patients, most patients were HFrEF (n=64, 71.9%), and 25(28.1%) were HFpEF. Patients with heart failure and reduced ejection fraction (HFrEF) were more likely to have thyroid dysfunction than those with preserved ejection fraction (p = 0.012). Regarding comorbidities among heart failure patients with thyroid dysfunction, approximately half of the patients had hypertension (40.4%). Conclusion Thyroid problems are one of the most prevalent endocrine abnormalities in our practice. Subclinical hypothyroidism was the most common type of thyroid dysfunction among this population. We suggest that thyroid function be evaluated with cardiac function in patients with heart failure and followed up and treated together with heart failure.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 93%

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Prevalence of Thyroid Dysfunction Among Patients with Heart Failure at a Tertiary Hospital in Mogadishu, Somalia

Mohamud¹,

İbrahim²,

Ahmed³

et al. 2022

IJGM

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“…Alteration in thyroid status is known to have deleterious effects on heart. [26] Among the endocrine diseases associated with CABG, thyroid dysfunction accelerates the risk factors in multiple and complex ways. [27] Thyroid disorders are frequently observed endocrine disease in India and worldwide.…”

Section: Discussionmentioning

confidence: 99%

How widespread is Thyroid Disorders among Patients undergoing Coronary Artery Bypass Grafting? A Study from Tertiary Care Hospital

Kahol¹,

Kathait²,

Mishra³

et al. 2022

APJHS

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Coronary artery bypass grafting (CABG) is the most commonly performed cardiac procedure and thyroid disorders (hypothyroidism and hyperthyroidism) are the most widespread endocrine diseases. Till date, there is no Indian study pertaining to prevalence of thyroid disorders among subjects undergoing CABG. The aim of this study was to determine the prevalence of thyroid disorders among subjects undergoing CABG in a tertiary care hospital. This is a prospective observational hospital-based study having 560 subjects who underwent CABG. Pre-operative thyroid tests were conducted of all the subjects. On the basis of this test, subjects were divided into groups, “Euthyroid” (normal thyroid status) and Thyroid subjects, that is, Subclinical Hypothyroidism (SCHypo), Overt Hypothyroidism (OVHypo), Subclinical Hyperthyroidism (SCHyper), and Overt Hyperthyroidism (OVHyper), based on thyroid function test. The proportion of the disorders was calculated. The study population included 560 subjects (Males: 457 females: 103). The overall prevalence of thyroid function abnormalities was 41.07%. The SCHypo was the most pervasive thyroid disorder (33.75%), followed by SCHyper (4.28%), OVHypo (2.32%), and OVHyper (0.7%). Highest number of thyroid subject (57.8%) was in 40–59 age group and lowest (0.86%) in 18–39. Thyroid was more prevalent among females (45/103) than in males (185/457). Among subjects undergoing CABG, SCHypo was most common followed by SCHyper, OVHypo, and OVHyper. Among the subjects undergoing CABG, maximum thyroid cases are in the age group of 60–79 with female preponderance.

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Frequency and Relevance of Thyroid Dysfunction in Patients with Chronic Heart Failure: A Cross Sectional Study at Yaoundé Central Hospital, Cameroon

Cited by 2 publications

References 0 publications

Prevalence of Thyroid Dysfunction Among Patients with Heart Failure at a Tertiary Hospital in Mogadishu, Somalia

Prevalence of Thyroid Dysfunction Among Patients with Heart Failure at a Tertiary Hospital in Mogadishu, Somalia

How widespread is Thyroid Disorders among Patients undergoing Coronary Artery Bypass Grafting? A Study from Tertiary Care Hospital

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