Frequency and Sensitivity of Extended Spectrum Beta-Lactamase Positive Organisms  in a Secondary and Tertiary Level Hospital Network in Dhaka

Asna, Shah Md Zahurul Haque; Akhter, Shameem; Rahman, Mahdia; Mohammad, Najib; Hafez, M A

doi:10.3329/jemc.v5i2.23377

Cited by 4 publications

(6 citation statements)

References 14 publications

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“…[1][2][3][4][5][6]9,15 In the current study, almost two-thirds of UTI cases were due to ESBL-positive organisms. In four different studies done in Bangladesh over the preceding years by Rahman MM et al 5 , Rahman MR et al 9 , Asna SMHZ et al 6 and Iqbal S et al 7 revealed up to 60% of all UTI cases were due to ESBL-positive organisms. In different studies in India 10 , Nepal 16 , Iran 17 and Turkey 18 up to 48% of UTI cases were due to ESBL-positive organisms.…”

Section: Discussionmentioning

confidence: 96%

“…10,[16][17][18][19] Antibiotic sensitivity patterns were also similar. [6][7][8][9][10][16][17][18] Current study had some limitations. It was a single center study, comprising small number of study population over a short period of time and most of our study participants were diabetic.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4] In Bangladesh, only a few studies were reported on ESBL-positive organisms, mostly describing their prevalence and antibiotic sensitivity patterns. [5][6][7][8][9] Diabetes mellitus (DM), past history of UTI and prior antibiotic use are reported risk factors for UTI due to ESBL-positive organisms. 10,11 In this study, we have tried to evaluate the frequency of UTI due to ESBL-positive Escherichia coli and Klebsiella pneumoniae, their antibiotic sensitivity patterns and risk factors.…”

Section: Introductionmentioning

confidence: 99%

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Frequency, Risk Factors and Antibiotic Sensitivity Pattern of Extended-Spectrum Beta-Lactamase Producing Escherichia coli and Klebsiella pneumoniae Causing Urinary Tract Infection: Experience from a Tertiary Care Hospital of Bangladesh

et al. 2017

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Frequency, Risk Factors and Antibiotic Sensitivity Pattern of Extended-Spectrum Beta-Lactamase Producing Escherichia coli and Klebsiella pneumoniae Causing Urinary Tract Infection: Experience from a Tertiary Care Hospital of Bangladesh

et al. 2017

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“…Again, most of the studies done in Bangladesh, concentrate on a single disease, pathogen, or specimen. [37][38][39][40][41][42][43][44][45][46][47][48][49][50][51] But, a single organism can cause different types of infection, at different sites and can cause different diseases. For example, E. coli can cause gastroenteritis, sepsis, UTI, even meningitis.…”

Section: Introductionmentioning

confidence: 99%

Prevalent Bacteria and Their Sensitivity and Resistance Pattern to Antibiotics: A Study in Dhaka Medical College Hospital

Hossain

Naher²,

Hasan

et al. 2017

J Dhaka Med Coll

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amikacin, moxifloxacin, imipenem, meropenem, piperacillin+tazobactum combination, vancomycin, doxycycline, tetracycline, tigecycline, nitrofurantoin, azactum, linezolid and 100% resistant to cefixime. Enterobacter was 100% sensitive to penicillin, amikacin, gentamicin, netilmicin, doxycycline, tetracycline, tigecycline and 100% resistant to cefixime, ceftazidime, ceftriaxone, cefepime, cotrimoxazole, levofloxacin, vancomycin. E. coli was 100% sensitive to imipenem, meropenem, vancomycin, tigecycline and 100% resistant to mecillinam, aztreonam. Klebsiella was 100% sensitive to flucloxacillin, colistin, vancomycin, tigecycline, linezolid and 100% resistant to nalidixic acid. Proteus was 100% sensitive to cephradine,

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“…This frequency is much higher than previous four reports from Bangladesh. 5,6,9,10 ESBL positive organisms are increasing in Korea and USA. Limitations of the study The study duration was short and sample size was small.…”

Section: Discussionmentioning

confidence: 99%

Frequency of Extended-Spectrum Beta-Lactamase Producing Organisms Causing Urinary Tract Infection and Their Antibiotic Sensitivity Pattern

et al. 2017

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Abstract Abstract AbstractBackgr Backgr Backgr Backgr Background: ound: ound:ound: ound: The spectrum of bacteria causing urinary tract infection (UTI) and their antibiotic sensitivity pattern is not uniform. Escherichia coli and Klebsiella sp. are two common organisms responsible for UTI through-out the world. The incidence of UTI due to infection with extended-spectrum beta-lactamase (ESBL) producing organisms are increasing. This study was aimed to describe the frequency of ESBL positive organisms causing UTI and their antibiotic sensitivity pattern. Methods:Methods: Methods: Methods: Methods: This cross-sectional study was done in the Department of Internal Medicine, BIRDEM General Hospital from January to April, 2016. Results:Results: Results: Results: Results: Total number of patients was 137 with females predominance (M:F ratio 1 : 3.7). Mean age was 60.3 ±11.7 years. Most patients (131, 95.6%) of the study population were diabetic and glycaemic control was poor (mean HbA1c 9.3 ±2.3) in these subjects. Common symptoms were fever, vomiting, increased urinary frequency, dysuria, suprapubic pain, and loin pain. Neutrophilic leukocytosis was common (94.9%). E. coli (73.7%) was the commonest aetiological agent followed by Klebsiella (8.8%), Enterococcus (4.4%), Citrobacter (3.6%), Staphylococcus aureus (3.6%), Acinetobacter (2.9%), Enterobacter (1.5%), and Pseudomonas (1.5%). Over half of E. coli and of Klebsiella sp. and 100% of Enterobacter organisms were ESBL positive. Imipenem (100%), amikacin, netilmycin,and nitrofurantoin were among the most sensitive antibiotics. Conclusion:Conclusion: Conclusion: Conclusion: Conclusion: More than half (71, 51.82%) of UTI cases were due to ESBL positive organisms. Imipenem, amikacin, netilmycin, and nitrofurantoin remain the drug of choice.

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Frequency and Sensitivity of Extended Spectrum Beta-Lactamase Positive Organisms in a Secondary and Tertiary Level Hospital Network in Dhaka

Cited by 4 publications

References 14 publications

Frequency, Risk Factors and Antibiotic Sensitivity Pattern of Extended-Spectrum Beta-Lactamase Producing Escherichia coli and Klebsiella pneumoniae Causing Urinary Tract Infection: Experience from a Tertiary Care Hospital of Bangladesh

Frequency, Risk Factors and Antibiotic Sensitivity Pattern of Extended-Spectrum Beta-Lactamase Producing Escherichia coli and Klebsiella pneumoniae Causing Urinary Tract Infection: Experience from a Tertiary Care Hospital of Bangladesh

Prevalent Bacteria and Their Sensitivity and Resistance Pattern to Antibiotics: A Study in Dhaka Medical College Hospital

Frequency of Extended-Spectrum Beta-Lactamase Producing Organisms Causing Urinary Tract Infection and Their Antibiotic Sensitivity Pattern

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