Frequency and Severity of Ovarian Hyperstimulation Syndrome (Ohss) Among Oocyte Donors According to Trigger Type and Number of Oocytes Retrieved

Tober, Diane; Richter, K.S.; Garibaldi, Cristina; Mostak, Kezia; Kokjohn, Shannon; Cool, Raquel; Zubizarreta, Cris; Villegas, Natalia; Cook, Katarina; Daneshmand, S.T.

doi:10.1016/j.fertnstert.2020.08.1332

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“…For donors, however, the more aggressive stimulation protocols that enable higher quantities of eggs to mature are also associated with greater risk for complications such as ovarian hyperstimulation syndrome (OHSS) and ovarian torsion, which may require removal of the ovary. Risks for severe OHSS—potentially a life‐threatening condition—appear to increase according to the number of eggs produced in a given cycle (Tober et al., 2020). Indeed, the Institute of Medicine recommends that cycles be canceled when a donor produces greater than 20 eggs, due to increased risk for severe ovarian hyperstimulation syndrome (Institute of Medicine, 2006).…”

Section: Gamete Markets and Regulations In The United States And Spainmentioning

confidence: 99%

“…Egg donation is a physically and emotionally demanding process, involving several weeks of hormone injections to create higher quantities of eggs, followed by surgery, usually under anesthesia, to remove each of the oocytes from the ovarian follicles. Medical risks—about which donors are minimally informed—can be substantial and increase according to the medication protocol used and the number of oocytes the donor produces (Tober, et al., 2021; Tober, Richter, et al., 2020).…”

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Eggonomics: Vitrification and bioeconomies of egg donation in the United States and Spain

et al. 2023

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Regulations governing assisted reproduction control the degree to which gamete donation is legal and how people providing genetic material are selected and compensated. The United States and Spain are both global leaders in fertility treatment with donor oocytes. Yet both countries take different approaches to how egg donation is regulated. The US model reveals a hierarchically organized form of gendered eugenics. In Spain, the eugenic aspects of donor selection are more subtle. Drawing upon fieldwork in the United States and Spain, this article examines (1) how compensated egg donation operates under two regulatory settings, (2) the implications for egg donors as providers of bioproducts, and (3) how advances in oocyte vitrification enhances the commodity quality of human eggs. By comparing these two reproductive bioeconomies we gain insight into how different cultural, medical, and ethical frameworks intersect with egg donor embodied experiences.

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Section: Gamete Markets and Regulations In The United States And Spainmentioning

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Eggonomics: Vitrification and bioeconomies of egg donation in the United States and Spain

et al. 2023

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Alignment between expectations and experiences of egg donors: what does it mean to be informed?

Tober¹,

Garibaldi

Blair

et al. 2021

Reproductive Biomedicine & Society Online

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This study evaluated the retrospective perceptions of egg donors regarding information communicated about immediate and long-term risks during the process of becoming an egg donor, and the alignment of that perception with their experiences and expectations of egg donation. Data were collected using an anonymous online survey. Egg donors' demographics, perceptions of being informed about immediate complications and long-term risks, and alignment between their expectations and experiences were analysed. In total, 375 current and former egg donors participated in an online survey about their decisions and experiences. Participants ranged in age from 18 to 57 years, with a median age of 24 years at first donation for compensated donors. The majority of the participants (81%) provided eggs in the USA, and 86.1% reported being compensated beyond direct reimbursement. Overall, 66% of egg donors surveyed reported feeling that their experiences matched their expectations based upon what they had been told during the informed consent process. While most participants (64.8%) felt well informed about potential short-term risks, 55.2% did not feel well informed about potential long-term risks. The findings indicate that while the majority of egg donors felt informed about immediate complications, there are gaps in knowledge about potential long-term risks. Results from this research provide insight into how egg donors understand risks and benefits, and can be used to improve counselling and informed consent forms and processes. The findings also indicate that longitudinal research on the health and well-being of egg donors is needed in order to improve informed consent.

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Frequency and Severity of Ovarian Hyperstimulation Syndrome (Ohss) Among Oocyte Donors According to Trigger Type and Number of Oocytes Retrieved

Cited by 2 publications

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Eggonomics: Vitrification and bioeconomies of egg donation in the United States and Spain

Eggonomics: Vitrification and bioeconomies of egg donation in the United States and Spain

Alignment between expectations and experiences of egg donors: what does it mean to be informed?

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