Frequency of abnormal pancreatic and biliary sphincter manometry compared with clinical suspicion of sphincter of Oddi dysfunction

Eversman, D.; Fogel, Evan L.; Rusche, Michael; Sherman, Stuart; Lehman, G.

doi:10.1016/s0016-5107(99)80011-x

Cited by 127 publications

(71 citation statements)

References 17 publications

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“…Comparing with previous reports on SOD prevalence, we found a higher prevalence in patients referred to ERCP (1,6,10,17,19,21) . We were surprised with such fi nding.…”

Section: Discussionsupporting

confidence: 64%

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Prevalence of sphincter of Oddi dysfunction in patients referred to endoscopic retrograde cholangiopancreatography

Líbera

Rodrigues

Guimarães

et al. 2007

Arq. Gastroenterol.

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-Background -Sphincter of Oddi manometry is the gold-standard method for sphincter of Oddi dysfunction. The prevalence of sphincter of Oddi dysfunction among patients referred to endoscopic retrograde cholangiopancreatography is largely unknown. Aim -To evaluate prospectively the prevalence of biliary sphincter of Oddi dysfunction (B-SOD) among Brazilian patients referred to endoscopic retrograde cholangiopancreatography and to study the safety of sphincter of Oddi manometry in this setting. Methods -Biliary sphincter of Oddi manometry was intended in 110 patients referred to endoscopic retrograde cholangiopancreatography. The number of attempts to obtain deep cannulation with the manometry catheter was recorded and patients were divided into two groups: up to 5 (easy cannulation) and >5 attempts (diffi cult cannulation). Results -Sphincter of Oddi manometry was successful in 71/110 patients (64.5%). Sphincter of Oddi dysfunction was found in 18/71 patients (25%). Endoscopic retrograde cholangiopancreatography fi ndings were: normal in 16, biliary stones in 39, malignant biliary strictures in 9 and benign biliary strictures in 7. There was no statistical difference in sphincter of Oddi dysfunction prevalence regarding disease, gender or diffi culty of cannulation. Only 2/71 patients developed post-procedure mild pancreatitis. Conclusions -We have found a high prevalence of sphincter of Oddi dysfunction in patients referred to endoscopic retrograde cholangiopancreatography. Gender, nature of disease or diffi culty of cannulation did not infl uence the prevalence of sphincter of Oddi dysfunction among these patients. Sphincter of Oddi manometry is a safe procedure for the evaluation of sphincter of Oddi dysfunction in patients referred to endoscopic retrograde cholangiopancreatography. HEADINGS -Sphincter of Oddi. Cholangiopancreatography, endoscopic retrograde. Bile ducts, physiopathology.

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“…Comparing with previous reports on SOD prevalence, we found a higher prevalence in patients referred to ERCP (1,6,10,17,19,21) . We were surprised with such fi nding.…”

Section: Discussionsupporting

confidence: 64%

“…Many studies in past decades made clear the relationship between the structural or functional obstruction of the sphincter and biliary or pancreatic-like pain. Such abnormality has been called sphincter of Oddi dysfunction (SOD) and it may be the etiology of post-cholecystectomy syndrome and/or recurrent idiopathic pancreatitis (6,19) .…”

Section: Introductionmentioning

confidence: 99%

Prevalence of sphincter of Oddi dysfunction in patients referred to endoscopic retrograde cholangiopancreatography

Líbera

Rodrigues

Guimarães

et al. 2007

Arq. Gastroenterol.

View full text Add to dashboard Cite

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“…In typeⅠSOD SOM will be abnormal in 75%-95% [15] . However, the frequency of abnormal biliary manometry varies from 28% to 60% for type Ⅱ patients and from 7 to 55% in type Ⅲ patients [16] . Various factors may explain the differences in frequencies of SOD in published reports.…”

Section: Sphincter Of Oddi Manometrymentioning

confidence: 99%

“…Also, the pressure in the pancreatic and biliary portions of the SO can vary so assessment of only one sphincter component, rather than both, will reduce the frequency of SOD detection. Current data suggests a discordance rate of between 35% and 65% [16,[18][19][20][21][22] . Therefore, both portions of the SO should be measured separately for a full assessment.…”

Section: Sphincter Of Oddi Manometrymentioning

confidence: 99%

“…This necessitates classifying each patient with respect to the pancreatic and biliary components of the SO and is one of the reasons some experts have called for a single overall classification system. When both sides of the sphincter are evaluated there is little difference between them in predicting [16] . Because SOM is technically difficult, invasive, has a variable diagnostic yield and has recognized complications, other indirect methods of evaluating SO function have been developed.…”

Section: Sphincter Of Oddi Manometrymentioning

confidence: 99%

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