Frequency of ambulatory care adverse events in Latin American countries: the AMBEAS/PAHO cohort study

Montserrat-Capella, Dolors; Suárez, Ma José Rodríguez; Ortíz, Lidia; Mira, José Joaquín; Duarte, Hernando Guillermo Gaitán; Revéiz, Ludovic; Group, on behalf of the AMBEAS; Cho, M.; Rodríguez, Hector P.; Milberg, Matías; Diéguez, Marta; Tristan, Michael P.; Granados, Rosario Inés; Puertas, BarrOs; Artaza, Osvaldo; Varella, D. A. A.; FitzGerald, John; Torres, Francesco; Iglesias, C; García, Lara; Lima, Raquel da Silva; Muñoz, Sebastián Andrés; Oliveira, Daniela; Valdés, Martín; Sagastuy, B.; Varela, Jesuina; Sousa, Filomena; Souza, Fernando Bernardi de; Torres, Renee E.

doi:10.1093/intqhc/mzu100

Cited by 30 publications

(38 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Of these, 17 were excluded due to having: an irrelevant setting that is not primary care, irrelevant interventions that were only addressing medication errors instead of reporting on drug related adverse events and describing only qualitative aspects of medication safety. The final search yielded a total of 19 citations for inclusion in this review, with two abstracts and 17 full papers [26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44]. A protocol detailing the methodology for the current review was followed [23].…”

Section: Resultsmentioning

confidence: 99%

“…However, the majority of the authors cited patient factors as the cause of ADRs such as advanced age, lack of patients' education and patients' comorbidities [4, 26, 28-31, 34-38, 40, 42]. Some studies mentioned drug related causes such as prescribers' errors, inconsistent consultation notes, incomplete physical examination, inappropriate follow up and monitoring errors as causes of ADRs [26,27,35,36,38,41,44]. Drug specific causes such as drug administration, dispensing errors, drug interactions and look alike medications were also mentioned by three studies [27,30,35,43].Allergic reactions were cited as the cause of ADRs in one study by Shehab et al [39] Iatrogenic causes was also cited by one study amongst other causes [42].…”

Section: Causes Of Adrs Reportedmentioning

confidence: 99%

See 1 more Smart Citation

Adverse drug reactions in primary care: a scoping review

Khalil

Huang

2020

BMC Health Serv Res

View full text Add to dashboard Cite

Background: Medication-related adverse events, or adverse drug reactions (ADRs) are harmful events caused by medication. ADRs could have profound effects on the patients' quality of life, as well as creating an increased burden on the healthcare system. ADRs are one of the rising causes of morbidity and mortality internationally, and will continue to be a significant public health issue with the increased complexity in medication, to treat various diseases in an aging society. This scoping review aims to provide a detailed map of the most common adverse drug reactions experienced in primary healthcare setting, the drug classes that are most commonly associated with different levels/types of adverse drug reactions, causes of ADRs, their prevalence and consequences of experiencing ADRs. Methods: We systematically reviewed electronic databases Ovid MEDLINE, Embase, CINAHL Plus, Cochrane Central Register of Controlled Trials, PsycINFO and Scopus. In addition, the National Patient Safety Foundation Bibliography and the Agency for Health Care Research and Quality and Patient Safety Net Bibliography were searched. Studies published from 1990 onwards until December 7, 2018 were included as the incidence of reporting drug reactions were not prevalent before 1990. We only include studies published in English. Results: The final search yielded a total of 19 citations for inclusion published over a 15-year period that primarily focused on investigating the different types of adverse drug reactions in primary healthcare. The most causes of adverse events were related to drug related and allergies. Idiosyncratic adverse reactions were not very commonly reported. The most common adverse drug reactions reported in the studies included in this review were those that are associated with the central nervous system, gastrointestinal system and cardiovascular system. Several classes of medications were reported to be associated with adverse events. Conclusion: This scoping review identified that the most causes of ADRs were drug related and due to allergies. Idiosyncratic adverse reactions were not very commonly reported in the literature. This is mainly because it is hard to predict and these reactions are not associated with drug doses or routes of administration. The most common ADRs reported in the studies included in this review were those that are associated with the central nervous system, gastrointestinal system and cardiovascular system. Several classes of medications were reported to be associated with ADRs.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Causes Of Adrs Reportedmentioning

confidence: 99%

Adverse drug reactions in primary care: a scoping review

Khalil

Huang

2020

BMC Health Serv Res

View full text Add to dashboard Cite

show abstract

“…This concern was first discussed in studies published in the 1970s, showing that adverse events are present in hospitals in several countries, constituting a global public health problem (1)(2)(3)(4)(5) . The main publication was the book titled To Err is Human: Building a Safer Health Care System, in 2000, which stated that, in the United States of America (USA), between 44,000 and 98,000 people die every year from errors associated with health treatment and health care provided in hospitals, caused by faulty systems, processes and conditions that lead people to make mistakes or fail to prevent them (6) .…”

Section: Introductionmentioning

confidence: 99%

Cultura de segurança do paciente em unidade de Transplante de Medula Óssea

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Although the frequency of near misses in clinical practice is difficult to specify, the frequency of adverse events at hospitals in developed countries has been established at approximately 9% [1]; in developing countries, it increases to approximately 10.5% [2]. In ambulatory care, the prevalence of adverse events has been confirmed to be approximately 2% [3-4] and 5%, respectively [5]. One-half of these adverse events are usually considered to be preventable [1].…”

Section: Introductionmentioning

confidence: 99%

The Second Victim Phenomenon After a Clinical Error: The Design and Evaluation of a Website to Reduce Caregivers’ Emotional Responses After a Clinical Error

Mira¹,

Carrillo²,

Guilabert³

et al. 2017

J Med Internet Res

View full text Add to dashboard Cite

BackgroundAdverse events (incidents that harm a patient) can also produce emotional hardship for the professionals involved (second victims). Although a few international pioneering programs exist that aim to facilitate the recovery of the second victim, there are no known initiatives that aim to raise awareness in the professional community about this issue and prevent the situation from worsening.ObjectiveThe aim of this study was to design and evaluate an online program directed at frontline hospital and primary care health professionals that raises awareness and provides information about the second victim phenomenon.MethodsThe design of the Mitigating Impact in Second Victims (MISE) online program was based on a literature review, and its contents were selected by a group of 15 experts on patient safety with experience in both clinical and academic settings. The website hosting MISE was subjected to an accreditation process by an external quality agency that specializes in evaluating health websites. The MISE structure and content were evaluated by 26 patient safety managers at hospitals and within primary care in addition to 266 frontline health care professionals who followed the program, taking into account its comprehension, usefulness of the information, and general adequacy. Finally, the amount of knowledge gained from the program was assessed with three objective measures (pre- and posttest design).ResultsThe website earned Advanced Accreditation for health websites after fulfilling required standards. The comprehension and practical value of the MISE content were positively assessed by 88% (23/26) and 92% (24/26) of patient safety managers, respectively. MISE was positively evaluated by health care professionals, who awarded it 8.8 points out of a maximum 10. Users who finished MISE improved their knowledge on patient safety terminology, prevalence and impact of adverse events and clinical errors, second victim support models, and recommended actions following a severe adverse event (P<.001).ConclusionsThe MISE program differs from existing intervention initiatives by its preventive nature in relation to the second victim phenomenon. Its online nature makes it an easily accessible tool for the professional community. This program has shown to increase user’s knowledge on this issue and it helps them correct their approach. Furthermore, it is one of the first initiatives to attempt to bring the second victim phenomenon closer to primary care.

show abstract

Frequency of ambulatory care adverse events in Latin American countries: the AMBEAS/PAHO cohort study

Abstract: The frequency of AE in ambulatory settings in LA is in the high-frequency range of research focused on the prevalence of AEs. Fifty percent was preventable. This study provides an approach for assessing the frequency and preventability of AE in order to enhance patient safety in LA.

Cited by 30 publications

References 31 publications

Adverse drug reactions in primary care: a scoping review

Adverse drug reactions in primary care: a scoping review

Cultura de segurança do paciente em unidade de Transplante de Medula Óssea

The Second Victim Phenomenon After a Clinical Error: The Design and Evaluation of a Website to Reduce Caregivers’ Emotional Responses After a Clinical Error

Contact Info

Product

Resources

About