Frequency of Atrial Tachyarrhythmias in Patients Treated by Cardiac Resynchronization (from the Prospective, Multicenter Mona Lisa Study)

Marijon, Éloi; Jacob, Sophie; Mouton, Elisabeth; Defaye, Pascal; Piot, Olivier; Delarche, Nicolas; Dennetiere, S.; Galley, D.; Franc, P. Le; Appl, Ursula; Guyomar, Yves; Albenque, Jean Paul; Chevalier, Philippe; Boveda, Serge

doi:10.1016/j.amjcard.2010.04.025

Cited by 16 publications

(7 citation statements)

References 20 publications

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“…The prevalence of AF in patients with heart failure (HF) is linked to the severity of heart disease: 5% in New York Heart Association (NYHA) class I as compared with 25–50% in NYHA class III/IV patients. Marijon et al 2 analyzed the incidence of AF in CRT patients in a prospective study and found that 34 of 173 (27.5%) patients developed paroxysmal AF during a follow‐up of 9.9 ± 3.6 months. About half of the AF patients had a past history of AF.…”

Section: Incidence and Prognosismentioning

confidence: 97%

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Cardiac Resynchronization and Atrial Fibrillation: What's New?

Barold

Herweg

2012

Pacing Clinical Electrophis

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atrial fibrillation, congestive heart failure, crtContemporary cardiac resynchronization therapy (CRT) devices are equipped with reliable and extensive diagnostic and memory features yielding full disclosure of the frequency, duration, and overall burden of atrial tachyarrhythmias.These advanced diagnostic features have demonstrated the high frequency of symptomatic and asymptomatic atrial arrhythmias, mostly atrial fibrillation (AF) in CRT patients. The loss of atrial transport function and associated tachycardia frequently result in deterioration of cardiac function and clinical deterioration. AF compromises CRT delivery due to RR interval variability and competing tachycardia, and may even result in excessive rapid ventricular pacing during atrial tracking. Atrial arrhythmias represent an important cause of poor long-term CRT benefit and prognosis unless aggressive efforts are made to slow the ventricular rate (VR). Over the last 3-5 years many important reports have addressed the diagnosis and treatment of atrial tachyarrhythmias in CRT patients. These new developments and their clinical implications form the basis of this review. Because the overwhelming majority of arrhythmias consist of AF, we shall refer, as do many workers, to atrial tachyarrhythmias simply as AF. [1][2][3][4] Although approximately 25% of patients undergoing CRT have permanent AF, 5,6 virtually all the randomized CRT trials have excluded patients with preexisting permanent AF. Evidence from relatively small studies have suggested that the CRT benefit in AF is comparable (or somewhat attenuated) to that seen in sinus rhythm provided the VR is controlled with digoxin and β-blockers. 7-11 A recent meta-analysis of 23 observational studies in a total of 7,495 patients (25.5% in AF) followed for 33 months showed that AF was associated with a higher risk of nonresponders (P = 0.001) and all-cause mortality (P = 0.015). 12 Ablation of the atrioventricular Address for reprints: S.

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Section: Incidence and Prognosismentioning

confidence: 97%

“…These new developments and their clinical implications form the basis of this review. Because the overwhelming majority of arrhythmias consist of AF, we shall refer, as do many workers, to atrial tachyarrhythmias simply as AF 1–4 …”

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confidence: 99%

Cardiac Resynchronization and Atrial Fibrillation: What's New?

Barold

Herweg

2012

Pacing Clinical Electrophis

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“…Isso ocorre devido a algumas peculiaridades relacionadas com a FA, tais como perda do sincronismo atrioventricular, maior risco de falha da estimulação ventricular sincronizada devido à dificuldade de controle da frequência cardíaca e ocorrência de batimentos de fusão e pseudofusão, maior incidência de disparo de choques de CDI (apropriados ou inapropriados), além de maior incidência de hospitalização e mortalidade. [186][187][188][189][190] Ritmo de FA ocorre em cerca de um quarto dos pacientes submetidos à TRC; entretanto, a maioria dos ensaios clínicos controlados e randomizados que demonstraram o benefício da TRC excluiu pacientes com FA (p. ex., CARE-HF, COMPANION).…”

Section: Paciente Com Fibrilação Atrialunclassified

Diretriz Brasileira de Dispositivos Cardíacos Eletrônicos Implantáveis – 2023

Teixeira¹,

Fagundes²,

Baggio³

et al. 2023

Arquivos Brasileiros De Cardiologia

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“…9,65 Furthermore, new-onset AF is relatively common in CRT recipients, likely due to its association with advanced HF. [66][67][68] The prognosis of AF in this setting remains uncertain; a MADIT-CRT substudy showed no difference in the clinical benefits obtained with CRT therapy in a cohort of patients with a history of intermittent AF/ATs versus controls. 66 However, a post-hoc analysis of the Comparison of Medical Therapy, Pacing, and Defibrillation in HF (COMPANION) trial suggested that AF patients did not draw any greater benefit from CRT in comparison with controls.…”

Section: Atrial Fibrillationmentioning

confidence: 99%

Advances in Cardiac Resynchronization Therapy

Jafferani

Leal

2019

J Innov Cardiac Rhythm Manage.

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The development of cardiac resynchronization therapy (CRT) has been crucial in reducing morbidity and mortality in patients with advanced heart failure. However, a significant proportion of patients who receive CRT fail to derive significant clinical benefits from this therapy. Successful CRT depends on a multitude of factors, including appropriate patient selection, left ventricular lead positioning, and postimplant management. Newer device-based algorithms, multipoint ventricular pacing, and the development of leadless CRT devices constitute important facets of both the present and near-future evolution of this therapy.

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Frequency of Atrial Tachyarrhythmias in Patients Treated by Cardiac Resynchronization (from the Prospective, Multicenter Mona Lisa Study)

Cited by 16 publications

References 20 publications

Cardiac Resynchronization and Atrial Fibrillation: What's New?

Cardiac Resynchronization and Atrial Fibrillation: What's New?

Diretriz Brasileira de Dispositivos Cardíacos Eletrônicos Implantáveis – 2023

Advances in Cardiac Resynchronization Therapy

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