Frequency of dog erythrocyte antigen 1.1 in 4 breeds native to different areas in<scp>T</scp>urkey

Ekiz, Elif Ergül; Arslan, Murat; Özcan, Mukaddes; Gültekin, Güldal İnal; Gülay, Özlem Yıldız; Kırmızıbayrak, Turgut; Giger, Urs

doi:10.1111/j.1939-165x.2011.00370.x

Cited by 17 publications

(11 citation statements)

References 22 publications

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“…Only a few studies have reported the risk for sensitization of an acute transfusional reaction. In 4 native breeds of Turkey a high sensitization risk after the first transfusion (14.4–35.6%) and the risk of an acute hemolytic reaction after second transfusion (7.2–25.3%) were found [32]. In Ibizan Hound and Galgos from Spain the sensitization risk after the first transfusion was similar to the data reported here [4, 30].…”

Section: Discussionsupporting

confidence: 86%

“…The prevalence for DEA 1 positive dogs found in this study was very similar to results 553/890 (62.0%) reported in another study carried out in Italy [29]. Furthermore, there have been other studies that showed similar results for DEA 1 positive dogs as in the case of Nigeria 71/178 (60.1%), Turkey 116/178 (65.2%), Portugal 156/274 (56.9%), and Spain 110/206 (53.4%) [4, 25, 28, 32]. Nevertheless, the first research about blood groups distribution in dogs from 1961 reported a lower prevalence of DEA 1 positive dogs 148/332 (44.6%) [13].…”

Section: Discussionmentioning

confidence: 54%

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Prevalence of Dog Erythrocyte Antigen 1 in 7,414 Dogs in Italy

Valentin

Gavazza

Lubas

2017

Veterinary Medicine International

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The study aim was to establish the prevalence of DEA 1, the most immunogenic and clinically important blood group in canine blood transfusion, in 7,414 dogs from Italy. The potential sensitization risk following a first transfusion and the acute reaction risk following a second transfusion given without a cross-matching and blood typing test were also calculated. Dogs tested were purebred (4,798) and mongrel (2,616); 38.8% were DEA 1 negative and 61.2% were DEA 1 positive. High prevalence for DEA 1 positive blood type was found in Ariegeois and English Setter, whereas German Shepherd and Boxer had higher DEA 1 negative blood type. Breeds with blood type never reported before included French Brittany Spaniel and Pug showing a high prevalence of DEA 1 positive type, while French Bulldog and West Highland White Terrier were more often DEA 1 negative. Just 48.8% of purebred and 13.9% of mongrel dogs were considered as prospective blood donors based upon their blood type. Most of the breeds had a sensitization risk of 20.0–25.0%. Rottweiler and Ariegeois had less risk of sensitization (9.4 and 4.2%) and the minor risk of an acute transfusional reaction (0.9–0.2%). The prevalence of DEA 1 positive and negative dogs in Italy agrees with most of the data already reported in the literature.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 54%

Prevalence of Dog Erythrocyte Antigen 1 in 7,414 Dogs in Italy

Valentin

Gavazza

Lubas

2017

Veterinary Medicine International

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“…The risk for sensitisation after first-time transfusion of untyped blood was found to be considerable but lower than that reported earlier from elsewhere (Ekiz et al . 2011 ; Ferreira et al . 2011 ).…”

Section: Discussionmentioning

confidence: 99%

A study on the prevalence of dog erythrocyte antigen 1.1 and detection of canine Babesia by polymerase chain reaction from apparently healthy dogs in a selected rural community in Zimbabwe

Dhliwayo

Makonese

Whittall

et al. 2016

J. S. Afr. Vet. Assoc.

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A study was carried out to determine the prevalence of blood group antigen dog erythrocyte antigen (DEA) 1.1 in mixed breed dogs in rural Chinamhora, Zimbabwe. DEA 1.1 is clinically the most important canine blood group as it is the most antigenic blood type; hence, DEA 1.1 antibodies are capable of causing acute haemolytic, potentially life-threatening transfusion reactions. In this study, blood samples were collected from 100 dogs in Chinamhora, and blood typing was carried out using standardised DEA 1.1 typing strips with monoclonal anti–DEA 1.1 antibodies (Alvedia® LAB DEA 1.1 test kits). Polymerase chain reaction for detecting Babesia spp. antigen was carried out on 58 of the samples. Of the 100 dogs, 78% were DEA 1.1 positive and 22% were DEA 1.1 negative. A significantly (p = 0.02) higher proportion of females (90.5%) were DEA 1.1 positive than males (69.0%). The probability of sensitisation of recipient dogs following first-time transfusion of untyped or unmatched blood was 17.2%, and an approximately 3% (2.95%) probability of an acute haemolytic reaction following a second incompatible transfusion was found. Babesia spp. antigen was found in 6.9% of the samples. No significant relationship (χ2 = 0.56, p = 0.45) was found between DEA 1.1 positivity and Babesia spp. antigen presence. Despite a low probability of haemolysis after a second incompatibility transfusion, the risk remains present and should not be ignored. Hence, where possible, blood typing for DEA 1.1 is recommended. A survey of DEA 3, 4, 5 and 7 in various breeds is also recommended.

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“…DEA 1.1 is expressed in approximately 40–60 per cent of the general canine population. However, marked differences in DEA 1.1 frequencies among breeds and geographic locations have been reported (Novais and others 1999, van der Merwe and others 2002, Nottidge and others 2006, Gracner and others 2007, Hale and others 2008, Zubcic and others 2008, Iazbik and others 2010, Ergul Ekiz and others 2011, Ferreira and others 2011). …”

Section: Introductionmentioning

confidence: 98%

Prevalence of dog erythrocyte antigen 1.1 in galgos (Spanish greyhounds)

et al. 2014

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Dog erythrocyte antigen (DEA) 1.1 is the most clinically important blood group in dogs, as negative recipients for this group may develop a life-threatening acute haemolytic transfusion reaction if they receive several DEA 1.1 positive blood transfusions. Due to their physical features, galgos are frequently used as blood donors in clinical practice, however, there are no published data regarding the prevalence of DEA 1.1 in this breed. Expression of DEA 1.1 was determined in 118 galgos and 88 dogs of other breeds being screened as potential blood donors, using an immunochromatographic cartridge typing kit (Quick Test DEA 1.1, Alvedia, Lyon, France). Of the total dogs, 53.4per cent (110/206) were positive for DEA 1.1. The prevalence of DEA 1.1 positive blood among our population of galgos and other-breed dogs were 51.7 per cent (61/118) and 55.7 per cent (49/88), respectively. Potential risk of sensitisation in a recipient of other breed following non-typed blood transfusion using blood from galgos was 22.9 per cent. Due to the clinical significance of DEA 1.1 and the high prevalence of this blood group in galgos of Spain, we strongly recommend blood-typing for this group before administering any blood transfusion using galgos as donors, as with transfusions from other commonly used breeds.

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Frequency of dog erythrocyte antigen 1.1 in 4 breeds native to different areas inTurkey

Cited by 17 publications

References 22 publications

Prevalence of Dog Erythrocyte Antigen 1 in 7,414 Dogs in Italy

Prevalence of Dog Erythrocyte Antigen 1 in 7,414 Dogs in Italy

A study on the prevalence of dog erythrocyte antigen 1.1 and detection of canine Babesia by polymerase chain reaction from apparently healthy dogs in a selected rural community in Zimbabwe

Prevalence of dog erythrocyte antigen 1.1 in galgos (Spanish greyhounds)

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