Frequency of hepatitis C virus infection in Type 2 Diabetic patients

Ali, Niaz; Iqbal, Saba; Bashir, Fouzia; Tanveer, Shama; Khan, Muhammad Ibrahim; Ahmad, Shahzad

doi:10.53350/pjmhs2115103530

Cited by 3 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our finding is in concurrence with the results reported by Solomon and Mehta (28,29). The prevalence of HCV infection has been described in different continents in Table 3 (11,(30)(31)(32)(33)(34)(35)(36)(37). In contrast, some studies have reported low prevalence of HCV infection in patients with type 2 diabetic (38)(39)(40)(41).…”

Section: Discussionsupporting

confidence: 92%

“…However, the rate of HCV prevalence varies from 0.5% to 10% in different regions of the world (11). In Iran, the seroprevalence of HCV among blood donors is about 0.13% and in general population is less than 1% (12).…”

Section: Introductionmentioning

confidence: 99%

“…Liver transplantation may be required as a result of HCV infection (16). Moreover, the HCV infection may contribute to extrahepatic manifestations which involve rheumatologic, dermatologic, renal, hematologic, and endocrine abnormalities like diabetes mellitus (11,17). There are several reports on the prevalence of HCV infection among patients with diabetes mellitus in Iran, the results show great heterogeneity between 0-2.5% (18).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Frequency and genotype distribution of hepatitis C virus infection in patients with diabetes type 2 in Ahvaz, Iran

Makvandi

Azaran

Jalilian

et al. 2021

IJM

View full text Add to dashboard Cite

Background and Objectives: Diabetes is recognized as a great concern and a public health problem worldwide. Several factors including environmental and genetic factors have been involved. Recently, infectious agents such as hepatitis C virus (HCV) have been reported to be associated with diabetes. Thus, this study was conducted to determine the frequency of HCV infection among patients with diabetes type 2 in Ahvaz city, Iran. Materials and Methods: A case-control study design was conducted at Ahvaz Jundishapur University of Medical Sciences. A total of 600 study subjects were included in this research. All the patient sera were tested for Anti- HCV antibody, HBsAg, and HIV antibody. The sera of positive Anti-HCV antibody, were assayed for 5'- UTR and core regions of the HCV genome by Nested RT-PCR. Finally, the HCV genotyping was determined by sequencing. Results: The prevalence of HCV in type 2 diabetes and nondiabetic controls was 2% and 0.33%, respectively. The distribution of HCV genotypes among the HCV-positive patients were 3a (1.66%) and 1a (0.33%). Conclusion: To control and improve the treatment, the screening of HCV infection with anti-HCV antibody was followed by molecular techniques such as PCR and HCV genotyping which should be implemented for all patients with diabetes type 2.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Frequency and genotype distribution of hepatitis C virus infection in patients with diabetes type 2 in Ahvaz, Iran

Makvandi

Azaran

Jalilian

et al. 2021

IJM

View full text Add to dashboard Cite

show abstract

“…The findings of a second investigation were likewise similar [17]. HCV was also shown to be frequent among diabetics in a research by Ali et al [18]. The findings of the Knobler and Schattner study [19] also showed a strong link between HCV infection and Type 2 Diabetes mellitus.…”

Section: Discussionsupporting

confidence: 61%

In Type 2 Diabetic Patients Prevalence of Hepatitis C Virus Infection

Zahoor¹,

Shehzadi²,

Hussain³

2022

PJMHS

View full text Add to dashboard Cite

Objectives: Aims: To determine the prevalence of the hepatitis C virus in people with type 2 diabetes and to look for any links between the two Study Design: Descriptive studys Place and Duration: Rural Health Centre Vanike Tarar, Hafizabad. April 2021-Dec 2021 Methodology: A total of 120 people with type 2 diabetes were included in the study. Patient’s age ranged from 20 to 80 years. A specified Performa was used to record all of the relevant data. Complete data sets were analysed using SPSS 24.0. Results: There were 55% males and 45% female in the entire study. Out of 120 confirmed diabetic patients, 40 (33.3%) were seropositive for anti HCV antibodies while 80 (66.7%) were negative. The sero-prevalence of HCV in female was 21 (52.5%) while in male it was 19 (47.5%). Conclusion: Patients with Type 2 Diabetes mellitus are more likely to be infected with HCV, according to our research. Keywords: Diabetes mellitus , Hepatocellular Carcinoma, Chronic Hepatitis C

show abstract

“…It was previously shown that the higher risk of HCV infection in type 2 diabetic patients may be related to frequent parenteral exposure (self-monitoring of blood glucose, insulin injection, blood transfusion) (22,23). Moreover, blood transfusion, mother-to-child transmission, non-sterile medical procedures and traditional practices (scarification, tattoo, and circumcision) were considered as common routes of HCV infection in Sub-Saharan Africa, despite the absence of confirmatory studies (16,24).…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of hepatitis C virus infection in patients with type 2 diabetes mellitus is associated with increased age in sub-Saharan Africa: Results from a cross-sectional comparative analysis

Feutseu

Kowo

Boli

et al. 2023

Front. Gastroenterol.

View full text Add to dashboard Cite

BackgroundSeveral epidemiological studies have established the association between hepatitis C virus (HCV) infection and type 2 diabetes mellitus (T2DM). However, the determinants and reasons for the high prevalence of HCV infection in people with T2DM are not well understood especially in sub-Saharan African populations. In this study, we aimed to assess determinants of the association between HCV infection and T2DM.MethodsWe performed a cross-sectional study amongst 442 T2DM patients recruited from an out-patient adult diabetes clinic in a tertiary hospital and 442 non-diabetic controls recruited from the general population. Serological testing for HCV antibody was performed using standard ELISA technique. Anti-HCV antibody prevalence was reported by age group in participants with diabetes and the non-diabetic controls. Logistic regression was used to examine for factors associated with the HCV infection in patients with diabetes.ResultsWe reported an overall HCV prevalence of 11.5% [95% CI: 9.4-13.6] irrespective of diabetes status in this study. The seroprevalence of HCV infection in diabetics patients was 17.6% [95% CI: 14.0-21.2] compared to 5.5% [95% CI: 3.4-7.6] in non-diabetics (p< 0.001). We did not find a significant HCV seropositivity difference in diabetic patients with common risk factors of HCV infection. When investigating the HCV seroprevalence by age group in diabetic and non-diabetic patients, no case of HCV infection was found in patients less than 30 years old while the highest HCV seropositivity was reported in patients older than 60 years (36.7% T2DM and 11.1% for non-diabetics) followed by the patients belonging to 50-59 years age group (16% in T2DM and 5.8% in non-diabetics) and those in 40-49 years age group (4.4% in diabetic, 0.8% in non-diabetic). To support this finding, in a multivariate logistic regression, only diabetic patients belonging to age group > 65 years had a significant risk (OR: 16.7 [95% CI: 1.7-160.0]) to acquire HCV infection.ConclusionThe seroprevalence of HCV infection is higher among T2DM adult patients than in non-diabetic patients, and is associated with increased age. This age-dependent association may suggest a generational exposure that may no longer exist overtime.

show abstract

Frequency of hepatitis C virus infection in Type 2 Diabetic patients

Cited by 3 publications

References 0 publications

Frequency and genotype distribution of hepatitis C virus infection in patients with diabetes type 2 in Ahvaz, Iran

Frequency and genotype distribution of hepatitis C virus infection in patients with diabetes type 2 in Ahvaz, Iran

In Type 2 Diabetic Patients Prevalence of Hepatitis C Virus Infection

Seroprevalence of hepatitis C virus infection in patients with type 2 diabetes mellitus is associated with increased age in sub-Saharan Africa: Results from a cross-sectional comparative analysis

Contact Info

Product

Resources

About