FREQUENCY OF HYPERURICEMIA IN TYPE 2 DIABETES MELLITUS PATIENTS WITH BMI >23 KG/M2- STUDY AT A TERTIARY CARE HOSPITAL

Abstract

OBJECTIVE: To determine the frequency of hyperuricemia in type 2 diabetes mellitus (T2DM) patients with BMI >23 kg/m2 MATERIALS AND METHODS: This descriptive study was conducted from February 2020 to September 2021. All patients with Type 2 Diabetes Mellitus (T2DM )with body mass index (BMI) >23 kg/m2 were assessed for hyperuricemia through Roche Cobas 6000 series C501 in MTI Hayatabad Medical Complex’s laboratory. RESULTS: Total number of patients was 300, out of which 60 % were males. The studied population has a mean age of 59 (SD =±7) years, mean systolic blood pressure was 151 (SD = ±17) mmHg, mean duration of T2DM was 13 (SD = ±4) years, mean HbA1c was 10.9 (SD = ±2.5) %, mean BMI was 28.8 (SD = ±3.1) kg/m2 and mean serum uric acid was 5.7 (SD=±1.3) mg/dl. The overall prevalence of Hyperuricemia was 47% (36.7 % males and 62.5% females). Of those with hyperuricemia, 73 % were also found to have hypertension. Results showed that patients with hyperuricemia belonged to older age, and have higher Systolic blood pressure, raised BMI, and HbA1c. The mean differences were considered statistically significant with a p-value < 0.05 by using an independent sample t-test. CONCLUSION: The current study demonstrated a higher prevalence of hyperuricemia in T2DM patients with BMI> 23 kg/m2. Patients with hyperuricemia had a higher mean HbA1c, higher mean BMI, and raised systolic component of blood pressure. KEY WORDS: BMI, Hyperuricemia, Hypertension, Type 2 diabetes mellitus, HbA1c