Frequency of obstructive coronary artery disease in patients undergoing valvular heart disease surgery.

Abstract

<jats:p>Objectives: To determine the frequency of obstructive coronary artery disease in patients undergoing valvular heart disease surgery. Study Design: Cross-sectional study. Setting: Department of Cardiology, Faisalabad Institute of Cardiology, Faisalabad. Period: Six months, from 02 February, 2017 to 01 August, 2017. Material &amp; Methods: After taking approval from hospital ethical committee, patients coming through outpatient department who fulfilled the inclusion criteria were enrolled and informed consent was taken from them. History of smoking, diabetes mellitus, renal dysfunction, dyslipidemia, hypertension and family history of coronary artery disease was assessed. Coronary angiography was performed by senior consultant interventional cardiologist for assessing obstructive coronary artery disease as per operational definition. All the information was collected on prespecified Performa. Results: In this study, out of 140 cases of valvular heart disease (VHD), 47.14%(n=66) were between 30-50 years of age whereas 52.86%(n=74) were between 51-70 years of age, mean ±sd was calculated as 51.71+9.09 years, 57.14%(n=80) were male while 42.86%(n=60) were female, frequency of obstructive coronary artery disease in patients undergoing valvular heart surgery was recorded as 29.3% (n=41) whereas 70.7% (n=99) had no such finding. Conclusion: The frequency of obstructive coronary artery disease was (29.3%) in patients undergoing valvular heart disease surgery. However, coronary artery disease was less frequent in rheumatic as compared to degenerative heart valve disease.</jats:p>

Obstructive Coronary Artery Disease in Patients Undergoing Rheumatic Valvular Heart Surgery

“…95% CI; 2.44-6.01], respectively. A study by Ahmad M et al13 in our local population reported obstructive CAD in 29.3% out of the study sample of 140 cases of VHD. Study further reported the incidence of obstructive CAD was 22.4% in patients with VHD of rheumatic etiology, close to over observation of 24.6%.…”

“…[8][9][10][11] The reported prevalence of concomitant CAD varies from the smallest of 9% to as high as 41% depending on the size of the sample, type of the VHD, and definition of CAD used by these studies. 5,12,13 One of the largest studies conducted in the United States of America included 5,360 patients of VHD without a known history of CAD, the prevalence of concomitant CAD was reported in around 19.3% in coronary CT/ diagnostic coronary angiography. 14 Considering the growing prevalence and prognostic implications of concomitant CAD in patients undergoing surgical procedures for VHD, a coronary angiographic assessment is recommended by the "American Heart Association / American College of Cardiology (AHA/ACC) guidelines", especially for the patients above 40 years of age.…”

“…15 Systematic and robust evidence regarding the prevalence of concomitant VHD and CAD are available for highincome countries, however, there is a dearth of reliable estimates for developing and under-developing countries such as Pakistan, where VHD of rheumatic etiology is more common. 13 It is of paramount importance to know the true prevalence of concomitant VHD and CAD for optimal management of the diseases. Additionally, an accurate assessment of burden of concomitant CAD in VHD patients can help in optimal utilization of hospital resources, surgical supplies, and services, especially high volume public sector hospitals like ours.…”

Enfermedad coronaria significativa en pacientes con estenosis aórtica severa en el Hospital Nacional Guillermo Almenara Irigoyen, Lima 2019 - 2020

“…El cateterismo cardiaco es un procedimiento médico que puede conllevar a riesgos para el paciente, pero su indicación en este grupo de pacientes está establecida como un protocolo y guía en el manejo de muchas patologías cardiacas. 16 La prevalencia de enfermedad coronaria significativa en pacientes con estenosis aortica severa del HNGAI-EsSalud, fue de 16.6% , realizado en dos años con un total de 120 pacientes comparado con el estudio de Ahmad y col(2020) 9 , del Instituto de Cardiología Faisalabad, (Pakistan). en un periodo de seis meses, un estudio de 140 casos, donde la prevalencia hallada de enfermedad coronaria significativa en pacientes con estenosis aortica severa fue 24.2 % .…”