Frequency of Oral and Para-Oral Lymphomas in Cairo Governorate: A Multi-Center Retrospective Study

Abstract

Aim: To describe the frequency of oral and para-oral lymphomas in Cairo governorate's educational hospitals and institutions between 2010 and 2019. Methods: Histopathological reports of patients diagnosed with oral and para-oral lymphomas from 2010 to 2019 were retrospectively retrieved from archives of educational hospitals and institutions in Cairo governorate. Data regarding age, gender, site and diagnosis was collected and analyzed using descriptive statistical methods. Results: 362 cases of lymphomas were found which constituted 2.86 % of oral and para-oral lesions. The mean age of patients was 54 (standard deviation 18.5), the median age was 56 (range 3.5-92 years). Tonsil was the most common site, followed by parotid gland. Intra-oral affection was less frequent, with the hard palate being the most common intra-oral site. Non-Hodgkin lymphoma was more common than Hodgkin lymphoma. Diffuse large B-cell lymphoma was the most prevalent histologic subtype. Conclusions:The findings of the current study were consistent with majority of other studies held in different geographic regions. Since there were no previous studies that described the epidemiology of oral and para-oral lymphomas in Egypt, this study serves as a stepping-stone towards understanding their prevalence in Egypt.