Frequency of translocation of <scp>USP</scp>‐6 in the aneurysmal bone cyst of the jaw

Obermeier, Katharina Theresa; Schmöckel, Elisa; Otto, Sven; Haidari, Selgai

doi:10.1111/jop.13393

J Oral Pathology Medicine

2022

DOI: 10.1111/jop.13393

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Frequency of translocation of USP‐6 in the aneurysmal bone cyst of the jaw

Katharina Theresa Obermeier¹,

Elisa Schmöckel²,

Sven Otto³

et al.

Abstract: Background This study aims to detect USP6 translocation in aneurysmal cysts located in the jaw and to give an overview of demographic data. Methods The present retrospective cohort study includes 10 patients who underwent surgery due to an aneurysmal cyst of the jaw in our hospital between 2002 and 2021. Unstained formalin‐fixed and paraffin‐embedded tissue sections cut at 4 μm thickness were subjected to USP6 FISH testing. Results All patients underwent surgical treatment. In four of ten patients (40%) USP‐6‐… Show more

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2024

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Bone Tumors of the Jaw – the “Blind Spot” for Radiologists Experienced with Tumors? – Part I

Grieser,

Hirsch,

Tödtmann

2024

Rofo

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Primary bone tumours of the jaw are rare tumoral entities and do substantially differ from other bone tumours of the human body with respect of their frequently encountered unusual radiological appearances. The reason for that may be confined to the co-existence of two closely neighbored but different anatomical structures (i.e., tooth-forming apparatus and jaw bones with adjacent gingiva) and some tumour pathologies which are nearly excusively encountered in the jaw bones only (e.g., ameloblastoma, ossifying fibroma, ghost cell carcinoma).This paper would like to highlight some basic principles of the diagnostic approach and possibilities of radiological differentiation of such tumour-suspicious changes within the gnathic system are elucidated and discussed.The paper presented here is substantially based on the most recent classification of odontogenic and maxillofacial tumours (5th edition, 2022) which serves as a scaffold for the selection of typical tumour entities. Due to the educational character of this paper, only important jaw tumours worth mentioning and their characteristics are subject to be extracted from the literature and further discussed.The main focus was put onto both the description of radiological tumoral appearance and the rational selection of a radiological diagnostic work-up. In order to better visualize this difficult field of tumour entities, much attention has been paid on a comprehensive pictorial essay.For radiologists, it is their foremast task to detect, describe, and to classify bone tumours of the jaw when they are found intentionally or accidentally, resp. A close co-operation with their clinical partners is of upmost importance to gain information about patient’s history and clinical presentation. It is readily reasonable that radiologists are mostly able to provide only a suggestion of the presented tumour entity but this expert opinion would be very helpful to further narrow down the list of potential differential diagnoses (e.g., differentiation of a cyst vs. solid tumour osteolysis, identification of jaw osteomyelitis vs. tumoral infiltration, recognizing of secondary tumour involvement of the jaw).

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Bone Tumors of the Jaw – the “Blind Spot” for Radiologists Experienced with Tumors? – Part I

Grieser,

Hirsch,

Tödtmann

2024

Rofo

View full text Add to dashboard Cite

show abstract

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Frequency of translocation of USP‐6 in the aneurysmal bone cyst of the jaw

Cited by 1 publication

References 24 publications

Bone Tumors of the Jaw – the “Blind Spot” for Radiologists Experienced with Tumors? – Part I

Bone Tumors of the Jaw – the “Blind Spot” for Radiologists Experienced with Tumors? – Part I

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