“…Changes in the epidemiology and characteristics of cardiogenic shock and acute HF have occurred in the last years. [10][11][12][13] Consistently, a systematic review and meta-regression of 285 studies, representing 15 million acute HF events, found a decline in 30-day mortality [odds ratio (OR) for a 10-year increment, 0.74, 95% confidence interval (CI) 0.61-0.91, P = 0.004] and 1-year mortality (OR 0.86, 95% CI 0.77-0.96, P = 0.007) after acute HF, in the last four decades. However, 30-day and 1-year readmission rates were unchanged.…”