“…Increased endorphins can affect the decrease in cortisol which has an impact on feeling relaxed, reducing tension, increasing feelings of pleasure, making a person more comfortable, and launching oxygen delivery to the muscles so that it can reduce levels of fatigue, anxiety, stress, and depression which will affect the quality of life of patients (7,9) Exercise can also maximize oxygen in the body which can reduce oxidative stress and produce energy that can reduce fatigue levels. Reduction of oxidative stress also has a good impact on improving quality of life and sleep quality (15,16). The results of interviews regarding the patient's condition after doing the exercise, on average, the patient stated that his body felt better, felt not stiff, and did not get tired easily so that he could carry out daily activities and rarely asked for help from others.…”