Fresh Ankle Osteochondral Allograft Transplantation for Tibiotalar Joint Arthritis

Meehan, Robert E.; McFarlin, Sarah; Bugbee, William D.; Brage, Michael E.

doi:10.1177/107110070502601002

Cited by 103 publications

(81 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our patient achieved an outstanding outcome as regards pain and mobility, with 94 points on the AOFAS scale for the left ankle and 92 for the right, although short-term results are similar to those of other authors. 18,20,21 Some authors believe ankle transplantation to be the primary treatment in osteochondral lesions of the astragalus and as an intervention to gain some time in salvage situations for post-traumatic osteoarthritides, secondary to arthritis, to osteonecrosis, or to haemophilic joint disease in young patients. Jeng et al 22 suggest that transplant candidates should be patients who are too young for a replacement arthroplasty, with a low body mass index, and normal limb alignment.…”

Section: Discussionmentioning

confidence: 99%

Fresh bipolar osteochondral allograft of the ankle. Review of the literature and case report of a young patient with bilateral post-traumatic osteoarthritis

Pimenta

Carvalho

Amado

2012

Revista Española de Cirugía Ortopédica y Traumatología (English

View full text Add to dashboard Cite

Objectives: The treatment of severe post-traumatic ankle arthritis remains a challenge nowadays. Since patients suffering from this pathology are mainly young and active people, a correct reconstruction, if possible, of the articular cartilage defects of the tibiotalar joint is very important to achieve a good result. Fresh bipolar osteochondral allograft (FBOA) is a promising operative technique, as an alternative to arthrodesis and total ankle replacement, in pain relief, restoration of function and indefinite delay of arthritic disease progression. Methods: The authors made a review of the literature and present a case report of a young 30-year-old man, with bilateral post-traumatic osteoarthritis of the ankle, treated with (FBOA). The patient was evaluated clinically and radiographically monthly. Results: Pain relief and postoperative function was significantly improved reaching 94 points in the left ankle (preoperative of 40 points), and 92 points in the right ankle (preoperative 42 points) AOFAS score. Conclusions: Fresh tibiotalar allografting seems to be a good alternative to arthrodesis and prosthetic replacement, in the treatment of ankle arthropathy and big articular cartilage defects mainly in young and active patients. This procedure achieves a good pain relief, maintaining functional joint motion and decreasing the risk of adjacent joint arthritis. © 2011 SECOT. Published by Elsevier España, S.L. All rights reserved. Aloinjerto osteocondral bipolar fresco del tobillo. Revisión de la literatura y presentación del caso de un paciente joven con artrosis bilateral postraumática ResumenObjetivo: El tratamiento de la artrosis postraumática grave del tobillo sigue siendo un reto en nuestros días. Dado que los pacientes afectos de esta afección son frecuentemente jóvenes y activos, la reconstrucción apropiada de los defectos articulares de la articulación tibioastragalina, si es posible, es muy importante para obtener un buen resultado. Los aloinjertos osteocondrales bipolares frescos (ABOF) constituyen una técnica quirúrgica prometedora, como una alternativa a la artrodesis o a la artroplastia de tobillo en cuanto al alivio de dolor, recuperación funcional y retraso de la progresión a la artrosis. Método: Se realiza una revisión de la literatura y se presenta el caso de un paciente varón de 30 años con artrosis bilateral postraumática del tobillo tratado con ABOF; el paciente fue revisado clínica y radiográficamente cada mes durante 15 meses.Resultados: Tanto el dolor como la función post-operatoria mejoraron de forma significativa, alcanzando 94 puntos en el tobillo izquierdo (puntuación preoperatoria de 40 puntos) y 92 puntos en el tobillo derecho (puntuación preoperatoria de 42 puntos).Conclusiones: El aloinjerto tibio-astragalino fresco parece ser una buena alternativa a la artrodesis o a la artroplastia en el tratamiento de la artropatía degenerativa del tobillo y de los defectos condrales articulares, principalmente en pacientes jóvenes y activos. Esta técnica consigue un buen alivio del dol...

show abstract

Section: Discussionmentioning

confidence: 99%

Fresh bipolar osteochondral allograft of the ankle. Review of the literature and case report of a young patient with bilateral post-traumatic osteoarthritis

Pimenta

Carvalho

Amado

2012

Revista Española de Cirugía Ortopédica y Traumatología (English

View full text Add to dashboard Cite

show abstract

“…Of the 5 (45.5%) patients with failure, 3 of them had repeat allografting with success, 1 was revised to total ankle arthroplasty while the other has had no further surgery. They concluded that poor results occurred in ankles with mismatch of size and graft thickness (<7mm) [61].…”

Section: Allograft Ankle Arthroplastymentioning

confidence: 99%

“…It involves replacing all or part of the arthritic ankle joint with a cadaveric OC allograft. This is a technically demanding procedure that requires an anatomically matching allograft in terms of side and size to host bone [59][60][61][62][63]. It is usually indicated for young active patients that are not suitable for total ankle arthroplasty.…”

Section: Allograft Ankle Arthroplastymentioning

confidence: 99%

Ankle Arthritis: An Evolution from Arthrodesis to Joint and Mobility Preservation

Tan¹

2013

Orthop Muscul Syst

View full text Add to dashboard Cite

Ankle arthritis is a debilitating condition. It can disrupt physical function and quality of life. Non surgical treatment includes pharmacological agents and orthoses. Surgical options range from arthrodesis to joint preservation techniques. Ankle arthrodesis is a reliable and effective treatment of choice for advanced ankle arthritis but has its limitations. Total ankle arthroplasty is fast gaining renewed interest as longer term outcome studies show good results coupled with improved implant and instrumentation designs. Osteotomies and arthroscopic debridement are increasingly popular techniques that are useful for joint preservation. Joint distraction arthroplasty and osteochondral allografting are also showing some promise. This article reviews the impact of ankle arthritis and treatment strategies available from joint sacrificing surgery to joint and mobility preservation.

show abstract

“…Meehan et al reported in their case series that all, but one patient (10/11) was found to have human leukocyte antigen cytotoxic antibodies following transplantation. 2 Furthermore, the one patient without antibodies was a renal transplant patient on immunosuppressive medications, and notably had an excellent result. It has been argued that while the articular cartilage portion of an allograft is immune-privileged, the underlying bone is not and contains cells that can elicit an immune response.…”

Section: Introductionmentioning

confidence: 99%

“…1,2 The operation involves replacing injured, diseased or missing regions of bone and articular cartilage with matched specimens from a cadaveric donor. The goal is to restore a congruent articular surface with viable hyaline cartilage, and osteochondral allograft has several advantages over the alternative surgical treatments for both conditions.…”

Section: Introductionmentioning

confidence: 99%

Osteochondral allograft transplantation in the ankle: a review of current practice

Fuchs¹,

Kadakia²

2015

ORR

View full text Add to dashboard Cite

Abstract:Osteochondral allograft transplantation is a technique that was first developed to treat cartilage pathology in the knee. Over the past 15 years, this technology has been translated to the treatment of osteochondral lesions and end-stage arthritis of the ankle. For osteochondral lesions of the talus or the tibia, a fresh osteochondral allograft transplant can be fashioned to match a specific defect and is useful for large, cystic or uncontained lesions. For a young patient with end-stage arthritis, bipolar fresh osteochondral allograft transplantation is a treatment alternative to ankle arthrodesis. Evidence for these operations is limited and consists primarily of case series, which have reported variable rates of success and in some cases high rates of complications and reoperations. Nevertheless, these techniques continue to evolve and should be considered as options for patients with certain conditions that are particularly challenging to treat.

show abstract

Fresh Ankle Osteochondral Allograft Transplantation for Tibiotalar Joint Arthritis

Abstract: Fresh osteochondral transplantation for tibiotalar joint arthritis is a promising alternative to arthrodesis and prosthetic replacement. Early results demonstrate successful outcomes and good pain relief in over half the patients in this series.

Cited by 103 publications

References 42 publications

Fresh bipolar osteochondral allograft of the ankle. Review of the literature and case report of a young patient with bilateral post-traumatic osteoarthritis

Fresh bipolar osteochondral allograft of the ankle. Review of the literature and case report of a young patient with bilateral post-traumatic osteoarthritis

Ankle Arthritis: An Evolution from Arthrodesis to Joint and Mobility Preservation

Osteochondral allograft transplantation in the ankle: a review of current practice

Contact Info

Product

Resources

About