Objective: To investigate the effects of wobbling angle on the stability measures of orthodontic mini-implants (OMIs) during insertion and removal procedures in artificial bone blocks. Materials and Methods: A total of 36 OMIs (self-drilling type, cylindrical shape, 7 mm in length, 1.45 mm in diameter) were allocated into three groups according to the amount of wobbling angle (W-0u, W-2u, and W-4u groups; N512 per group). The OMIs were installed and subsequently removed from artificial bone blocks (Sawbone) using a driving torque tester with a uniform speed of 28 rpm. Insertion peak time (IPT), maximum insertion torque (MIT), total insertion energy (TIE), near-peak insertion energy (NPIE), maximum removal torque (MRT), and near-peak removal energy (NPRE) were measured. Results: The W-4u group showed the longest IPT and highest TIE and NPIE, followed by the W-2u and W-0u groups (W-0u , W-2u , W-4u, all P , .001). The W-2u and W-4u groups showed significant increase in MIT compared with the W-0u group (W-0u , [W-4u,W-2u]; P , .001). Although there was no significant difference in NPRE among the three groups, the W-4u group showed a decrease in MRT compared with the W-0u and W-2u groups (W-4u , {W-2u,W-0u]; P , .05). Although the W-4u group showed a 14.5% (2.9 Ncm) increase in MIT compared with the W-0u group, there was only a 6% (1.3 Ncm) decrease in MRT from the W-0u group to the W-4u group. Conclusion: Slight wobbling during the OMI insertion procedure may be acceptable in terms of the stability measures of OMIs during insertion and removal procedures. (Angle Orthod.