Frictional properties of maxillofacial prosthetic elastomers

Andreopoulos, A. G.; Polyzois, Gregory

doi:10.1007/bf00121149

Cited by 5 publications

(6 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Polylactide (PLA) is a thermoplastic aliphatic polyester, which is widely used in packaging, medical, and agricultural applications, due to its degradability, biocompatibility, and renewability [1][2][3]. PLA can be synthesized by polycondensation of lactic acid, derived from starch fermentation, or ring-opening polymerization of its cyclic lactide (LA) dimer, where the latter approach is common for producing high molecular weight (MW) products.…”

Section: Introductionmentioning

confidence: 99%

Electrospinning of poly(l-lactide-co -dl-lactide) copolymers: Effect of chemical structures and spinning conditions

et al. 2013

View full text Add to dashboard Cite

Nanofibers of poly(L‐lactide‐co‐DL‐Lactide) (PDLLAx) copolymers with DL‐lactate (DLLA) contents of 0, 2.5, 7.5, and 50%, which exhibit strong structure/properties correlation, were fabricated by electrospinning. Effect of the copolymer structure and electrospinning conditions on morphology and properties of the fibers were examined by SEM, DSC, XRD, and tensile measurements. Bead‐free fibers of PDLLAx prepared from a DMF/CHCl3 mixed solvent are roughly 10‐times smaller in size (600–800 nm), with lower degree of surface porosity, compared to those of CHCl3. When CHCl3 is employed, an increase in size (2.4–5.5 μm) and surface porosity (0–45%) with relative humidity value is observed in crystallizable copolymers, whereas an amorphous copolymer shows a reverse trend. Thermal properties and chain arrangements of the electrospun fibers are critically affected by DLLA content of the copolymers and electrospinning conditions, as a result from interplay between intermolecular and intramolecular hydrogen bonding. Contents of crystalline domains and “physical crosslinks” generated from DL lactate segments are proposed as the origin of this phenomenon. Fiber mats of PDLLA with 50% DLLA content show a large improvement in all aspects of mechanical properties, which are suitable for various biomedical applications. POLYM. ENG. SCI., 54:472–480, 2014. © 2013 Society of Plastics Engineers

show abstract

Section: Introductionmentioning

confidence: 99%

Electrospinning of poly(l-lactide-co -dl-lactide) copolymers: Effect of chemical structures and spinning conditions

et al. 2013

View full text Add to dashboard Cite

show abstract

“…6 Among biodegradable polymers poly(lactid acid) (PLA) [both in the form of poly(L-lactid acid) (P(L)LA) and poly(D,Llactid acid) (P(D,L)LA)] appears as an interesting candidate for stent coating thanks to its biocompatibility, in fact in physiological conditions it undergoes biodegradation to lactic acid with L-lactic acid as a natural intermediate in carbohydrate metabolism. 7,8 In particular, P(D,L)LA has emerged as the material of choice in the field of drug-eluting stents coating as it is degraded faster than P(L)LA. Nevertheless P(D,L)LA coating has also some drawbacks, in fact, it is known to activate a local inflammatory response characterized by both platelet 9 and granulocyte 10 activation.…”

Section: Introductionmentioning

confidence: 99%

Poly (D,L) lactic acid blending with vitamin E increases polymer hemocompatibility: An hydrophilic effect

Renò

Paul

Rizzi

et al. 2012

J of Applied Polymer Sci

View full text Add to dashboard Cite

Biocompatible and resorbable polylactic acid (PLA) derived polymers are used for clinical applications. Antioxidant vitamin E (Vit.E) and vitamin E acetate (Vit.E Ac), a Vit.E commercial analog, were added to PLA during films preparation. Wettability, protein adsorption analysis, platelet adhesion and whole blood coagulation experiments highlighted that Vit.E incorporation improved PLA hemocompatibility. NMR analysis showed that Vit.E and Vit.E Ac blending differentially altered PLA polymer organization with Vit.E leading to the formation of microcavities, as observed by SEM analysis, while reducing surface hydrophobicity.

show abstract

“…Biodegradable carriers offer the advantages of bioresorption in the body that obviates removal operations, complete drug release, reduced foreign body reactivity and release kinetics that can be modulated via the degradation behaviour of the polymeric carrier. Various biodegradable carrier materials have been studied over the last decade based on natural polymers like collagen [6], calcium phosphates [7] or synthetic polymers [8,9], mainly derived from poly(hydroxy acid)s [10][11][12][13][14][15][16][17][18]. With the exception of collagen which has been available as collagen-gentamicin sponges for some years [6], none of these biodegradable materials have found broad clinical use and acceptance up to now.…”

Section: Introductionmentioning

confidence: 99%

Novel Polylactide‐Based Release Systems for Local Antibiotic Therapies

Vogt

Kühn

Ege

et al. 2003

Materialwissenschaft Werkst

View full text Add to dashboard Cite

Antibiotic delivery systems based on biodegradable polymers have found considerable interest for the local therapy of bone infections. In this study polylactide based polymer and composite delivery systems for the release of gentamicin have been fabricated from poly-L-lactides and a poly(L-lactide-co-D,L-lactide) as well as biodegradable inorganic fillers (calcium hydrogen phosphate, calcium sulfate dihydrate). The in vitro release profiles of the polymer delivery systems were characterized by an initial burst release followed by a sustained release of small gentamicin amounts up to 3 weeks. In the composite delivery systems a loss of retardation was observed with an increasing content of inorganic filler material. It was found that the in situ complex formation of gentamicin by adding defined amounts of sodium dodecyl sulfate represents a valuable tool to overcome this problem and to modulate the release profile of the delivery systems in a wide range. Under in vitro conditions, calcium sulfate dihydrate containing delivery systems are rapidly degraded in aqueous medium within several months. Based on these results, the developed composite delivery systems are promising candidates for the efficient treatment of bone infections.

show abstract

Frictional properties of maxillofacial prosthetic elastomers

Cited by 5 publications

References 11 publications

Electrospinning of poly(l-lactide-co -dl-lactide) copolymers: Effect of chemical structures and spinning conditions

Electrospinning of poly(l-lactide-co -dl-lactide) copolymers: Effect of chemical structures and spinning conditions

Poly (D,L) lactic acid blending with vitamin E increases polymer hemocompatibility: An hydrophilic effect

Novel Polylactide‐Based Release Systems for Local Antibiotic Therapies

Contact Info

Product

Resources

About