Friedel-Crafts Benzylation of 1,4-dialkoxybenzenes – Cleavage and Rearrangement of Esters and Methoxymethyl Ethers in ZnCl₂ Montmorillonite K10 Clay

Abstract

Benzylation of p-dialkoxybenzenes can be achieved through the use of modified montmorillonite K10 clay. For the first time, syntheses of nitro-diarylmethanes were obtained by Friedel-Crafts alkylation with good yields. In the case of p-methoxymethyl phenyl ether and phenyl ester, selectivity favoring Fries rearrangement over benzylation is reported.

Synthesis of Oligo(phenylene ethynylene)s with Dendrimer “Shells” for Molecular Electronics

“…Also, the first- and second-generation dendrimers were prepared as materials; the details are shown in the Supporting Information. Subsequently, the phenolic hydroxy group of hydroquinone ( 2 ) was protected with the MOM group to afford compound 3 in 75% yield, which was then treated with I 2 and Hg(OAc) 2 to provide compound 4 in 80% yield. Deprotection of 4 with HCl furnished the key intermediate diphenol 5 in 95% yield.…”

Toward a New Way for the Valorization of Miscanthus Biomass Produced on Metal-Contaminated Soils Part 2: Miscanthus-Based Biosourced Catalyst: Design, Preparation, and Catalytic Efficiency in the Synthesis of Moclobemide

“…The resulting solid was dried at 80 °C for 12 h, to provide 1.9036 g of a white powder. From this, 0.5036 g were used as such and constituted the homogenous catalyst (M1) and the remaining 1.5 g were supported on montmorillonite K10 to obtain 1.22 mmol Zn per g of support in dry methanol to provide the heterogeneous catalyst (MM1) [13]. Upon concentration in vacuo, MM1 was finally activated at 120 °C overnight.…”

Biomass of ryegrass from field experiments: toward a cost-effective and efficient biosourced catalyst for the synthesis of Moclobemide

“…After cooling, the mixture was filtered on celite and the filtrate was evaporated to dryness. The residue was dried at 80°C for 12 h and then mixed with montmorillonite K10 in dry methanol to obtain 1.22 mmol Zn per g of support (15). Activation of this catalyst was performed at 120°C overnight (15).…”