Ellipse center extract ion is the important basis of camera calib ration with circle arrays calibrat ion board, wh ich direct ly affects the measurement accuracy of mach ine vision system. A iming at the problem of high noise sensitivity of the most ellipse center extract ion methods, a high robust multi-ellipse center extraction method is proposed. The idea is to transform the problem of mult i-ellipse center extraction into the problems of ellipse sub-pixel edge segmentation and edge based ellipse center clustering. Firstly, the flowchart of the proposed method is introduced. Then, the theory of fuzzy quotient space is introduced to establish the dynamic granularity matrix space model, which describes image segmentation problem as the jump ing and transformat ion of the image by hierarchical structure. Finally, an adaptive multi-ellipse sub-pixel edge segmentation method and an optimal ellipse center ext raction method are proposed based on the dynamic granularity matrix space model. Experimental results sh ow that the proposed method has higher accuracy, robustness and lower camera calibration error. INDEX TERMS multi-ellipse center, dynamic granularity matrix space, sub-pixel edge segmentation, hierarchical structure, camera calibration.