Metaphor has been a powerful cognitive and strategic communication instrument of dominant participants in the pandemic discourse, which has already been attested by multiple studies conducted so far (e.g. Musolff et al., 2022; Nerlich, 2020; Olza et al., 2021; Semino, 2021; Silaški & Đurović, 2022a, 2022b; Wicke & Bolognesi, 2020). This paper deals with metaphors in the pandemic discourse in Serbia, which I define here as a public discourse of political elites and health experts used during 2020 and 2021 including both the primary pandemic discourse (public addresses of politicians and those of medical experts during the regular sessions of the national Crisis response team) as well as the secondary pandemic discourse (that of the media reporting on the Covid-19 pandemic). The paper is couched in the theoretical framework of Critical Metaphor Analysis (Charteris-Black, 2004, 2019, 2021; Musolff, 2006, 2016, 2019; Musolff et al., 2022), especially its strand that promotes a discourse approach to metaphors (Cameron & Deignan, 2006; Semino, 2008, 2020, 2021). The qualitative analysis of the data collected from various media outlets in Serbian (e.g. Danas, N1, RTS, Blic, Politika, Direktno, Mondo, NovaS, etc.) during 2020 and 2021 has shown that a number of different metaphors, those of war, sport, natural force / natural disaster, as well as a multitude of unconventional, creative and idiosyncratic metaphors, perform several strategic and intertwined functions in the pandemic discourse. These range from serving as an instrument of affective manipulation by communicating a sense of danger, uncertainty and threat coming from the virus, to legitimising the wanted course of action and concealing the responsibility of government officials and health experts, to being one of the useful tools for popularizing medical scientific discourse and making it understandable by the general public for the purpose of combatting a dangerous anti-vaccine rhetoric and boosting Covid-19 vaccine acceptance. Such multifunctionality of metaphors once again attests to their being a potent and persuasive tool of creating the desired realities in line with the needs and agendas of political elites.