2024
DOI: 10.1021/acsbiomaterials.4c00766
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From Chips-in-Lab to Point-of-Care Live Cell Device: Development of a Microfluidic Device for On-Site Cell Culture and High-Throughput Drug Screening

Yibo Feng,
Bingchen Che,
Jiahao Fu
et al.

Abstract: Live cell assays provide real-time data of cellular responses. In combination with microfluidics, applications such as automated and high-throughput drug screening on live cells can be accomplished in small devices. However, their application in point-ofcare testing (POCT) is limited by the requirement for bulky equipment to maintain optimal cell culture conditions. In this study, we propose a POCT device that allows on-site cell culture and highthroughput drug screening on live cells. We first observe that ce… Show more

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