2013
DOI: 10.1089/apc.2012.0419
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From Efficacy to Effectiveness: Facilitators and Barriers to PrEP Acceptability and Motivations for Adherence Among MSM and Transgender Women in New York City

Abstract: This study examined potential facilitators and barriers to pre-exposure prophylaxis (PrEP) use and their association with PrEP acceptability and motivations for adherence among 184 MSM and transgender women living in New York City. Participants were presented with educational information about PrEP and completed a computerized survey. Overall, 55.4% of participants reported willingness to take PrEP. The most highly endorsed barriers to PrEP use were health concerns, including both long-term impacts and short-t… Show more

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Cited by 321 publications
(270 citation statements)
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References 34 publications
(43 reference statements)
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“…52 Furthermore, as PrEP begins to play a more pivotal role in an integrated HIV prevention strategy, its effectiveness relies on its acceptability, adoption, and sustainability particularly among high-risk individuals. [53][54][55] Its success also hinges on mutual serostatus disclosure between sexually active partners so that HIV-negative partners are informed of the seropositivity of a partner and aware of their own HIV serostatus before they can make a decision to initiate PrEP.…”
Section: Discussionmentioning
confidence: 99%
“…52 Furthermore, as PrEP begins to play a more pivotal role in an integrated HIV prevention strategy, its effectiveness relies on its acceptability, adoption, and sustainability particularly among high-risk individuals. [53][54][55] Its success also hinges on mutual serostatus disclosure between sexually active partners so that HIV-negative partners are informed of the seropositivity of a partner and aware of their own HIV serostatus before they can make a decision to initiate PrEP.…”
Section: Discussionmentioning
confidence: 99%
“…[3][4][5] Commonly cited barriers to PrEP implementation include limited awareness about PrEP, concerns about side-effects, adherence, cost, access, low perceived risk of HIV acquisition, and stigma. 2,4,6,7 Whether and how these barriers affect PrEP uptake and PrEP clinical programs in real-world settings is unknown. Similarly, other than in efficacy trials that found that individuals on PrEP did not engage in higher risk behaviors after PrEP initiation, little is known about changes in sexual risk behaviors following PrEP initiation.…”
Section: 4mentioning
confidence: 99%
“…Previous research has demonstrated adoption of and intentions to use PrEP among MSM (Gamarel & Golub, 2015;Golub, Gamarel, Rendina, Surace, & Lelutiu-Weinberger, 2013;Young & McDaid, 2014). However, there is the tendency to recruit samples of participants in urban and suburban areas of the U.S., thus ignoring the unique experiences of MSM residing in more rural states.…”
mentioning
confidence: 99%