Industry 5.0 has created a more stable and networked industrial environment using the internet of things (IoT). Industry 5.0 creates a work environment where human-machine interaction is optimized for better performance by combining human cooperation with robots and intelligent equipment. Industrial internet of things (IIoT) includes various services in large settings, such as digital domains for company management, real-time production monitoring, and machinery condition tracking. Industry 5.0 aims to achieve the best possible balance between productivity and efficiency in various sectors, including heavy manufacturing, oil and gas, and warehouse management, which heavily rely on heavy gear. This chapter comprehensively explores the multiple dimensions of the IoT in Industry 5.0 used in intelligent manufacturing for fault screening and mechanical diagnosis and prognosis.