2024
DOI: 10.1002/cti2.1514
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From intramuscular to nasal: unleashing the potential of nasal spray vaccines against coronavirus disease 2019

Ge Jin,
Runze Wang,
Yi Jin
et al.

Abstract: Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has affected 700 million people worldwide since its outbreak in 2019. The current pandemic strains, including Omicron and its large subvariant series, exhibit strong transmission and stealth. After entering the human body, the virus first infects nasal epithelial cells and invades host cells through the angiotensin‐converting enzyme 2 receptor and transmembrane serine protease 2 on the host cell surface. The nasal… Show more

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