The COVID-19 outbreak has had considerably harsh impacts on the global economy, such as shutting down and paralyzing industrial production capacity and increasing the unemployment rate. For enterprises, relying on past experiences and strategies to respond to such an unforeseen financial crisis is not appropriate or sufficient. Thus, there is an urgent requirement to reexamine and revise an enterprise’s inherent crisis management architecture so as to help it recover sooner after having encountered extremely negative economic effects. To fulfill this need, the present paper introduces a fusion architecture that integrates artificial intelligence and multiple criteria decision making to exploit essential risk factors and identify the intertwined relations between dimensions/criteria for managers to prioritize improvement plans and deploy resources to key areas without any waste. The result indicated the accurate improvement priorities, which ran in the order of financial sustainability (A), customer and stakeholders (B), enablers’ learning and growth (D), and internal business process (C) based on the measurement of the impact. The method herein will help to effectively and efficiently support crisis management for an organization confronting COVID-19. Among all the criteria, maintaining fixed reserves was the most successful factor regarding crisis management.