From Surprise to Suspicion: Ovarian Metastases

Ortiz-Mendoza, Carlos Manuel; Catarino-Dircio, Arturo

doi:10.1007/s40944-016-0071-3

Cited by 1 publication

(1 citation statement)

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“…11 In an 82-year-old female patient with BD, a long-standing lesion may grow laterally to a size exceeding 3.5 cm. 18 BD of the breast is clinically manifested as a pruritic and scaly lesion over the unilateral nipple. 14 In addition, patients may present with scaling, crusting, pruritus, swelling, occasional bleeding, and inflammation of the nipple.…”

Section: Discussionmentioning

confidence: 99%

Bowen’s Disease of the Nipple and Areola: Case Report and Literature Review

Zhang¹,

Lü²,

Liu³

et al. 2023

CCID

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Introduction: Bowen's disease (BD) commonly occurs in sites of chronic sunlight exposure such as head, neck and extremities. It rarely distributes on the nipple and areola. Case Presentation: A 59-year-old female presented with crusted plaque on the right breast for over 1 month. Physical examination found an asymptomatic plaque (5 cm × 5 cm) with irregular shape on the right breast. Histopathological examination suggested irregularly acanthotic epidermis and atypical epidermal cells. Dermis showed inflammatory cell infiltration. Immunohistochemical staining showed negative staining for cytokeratin 7 and cytokeratin 20, and positive staining for Ki67 (60%). The mass was excised and no recurrence occurred in the follow-up. Additionally, we reviewed the literature about BD of the breast and summarized the clinical manifestations, histological features, and treatment options. Conclusion:We reported a rare BD case involving nipple and areola. Wide local excision and complete nipple excision are effective for patients with BD of the nipple and areola.

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Section: Discussionmentioning

confidence: 99%