From the archives of the AFIP. Genitourinary rhabdomyosarcoma in children: radiologic-pathologic correlation.

Agrons, Geoffrey A.; Wagner, B.; Lonergan, Gael J.; Dickey, Glenn E.; Kaufman, Michael S.

doi:10.1148/radiographics.17.4.9225391

Cited by 102 publications

(57 citation statements)

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“…4,44 Finally, in hyaline membrane disease of the neonate, it is possible that an immature lung, anatomically structured with small, wet, and homogeneous distal airways (pseudoglandular and saccular phases of development, hyaline membranes, and atelectasis), could induce massive internal reverberations with mechanisms like the ones observed in our experiment in the 3-dimensional layer of smaller bubbles. 45 Evidence found in the past and recent literature and the finding of different densities and arrangements of B-lines confirm the genetic hypothesis of Lichtenstein et al 8 to be reductive because it only includes a minority of cases of interstitial syndrome in a spectrum of acoustic representations ranging from septal syndrome to echographic white lung. 3,4,16,38 Although convincing in some cases of cardiogenic pulmonary edema, ULCs are rarely distributed so purely and regularly and are rarely able to signal an effective anatomic distance between interlobular septa, which, as we found, are actually separated by 10 to 30 mm.…”

Section: Discussionsupporting

confidence: 64%

Sonographic Interstitial Syndrome

Soldati¹,

Copetti

Sher

2009

Journal of Ultrasound in Medicine

225

172

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Objective. Ultrasound lung comets (ULCs) now have an acknowledged correlation with extravascular lung water, but they present in different orders and numbers in different pathologic pulmonary entities. How these artifacts are created is not yet known, and the literature gives discordant hypotheses. Understanding their formation is the first step in understanding lung disease. The purpose of this study was to show the morphologic and genetic variability of interstitial lung disease studied with echography and thus to propose a unitary mechanism for the formation of ULCs. Methods. This study included 3 parts: (1) a retrospective analysis of echographic lung images of patients with interstitial syndrome; (2) an analysis of the literature for definitions of the size of the pulmonary lobule; and (3) an experimental model of different air-water interfaces scanned with varying ultrasonic frequencies.Results. The retrospective analysis of echographic lung images included 176 patients with diffuse ULCs: 118 patients had acute pulmonary edema; 18 had acute lung injury/acute respiratory distress syndrome; and 40 were premature neonates with respiratory distress syndrome. Experimental models permitted us to discover that ring-down artifacts are produced only by single and double layers of bubbles in specific structural settings. Conclusions. Reverberation between bubbles with a critical radius seems to be at the origin of ring-down artifacts. Echographic manifestations of interstitial lung disease, whose genesis lies in the partial air loss of lobes and segments, are acoustic phenomena originating from variations in the tissue-fluid relationship of the lung. A correlation between anatomopathologic characteristics and structures of sonographic artifacts could allow more rapid and noninvasive diagnoses.

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Section: Discussionsupporting

confidence: 64%

Sonographic Interstitial Syndrome

Soldati¹,

Copetti

Sher

2009

Journal of Ultrasound in Medicine

225

172

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“…Although underlying the use of chemotherapy, bladder mass detected after macroscopic hematuria complicates the differential diagnosis in this case of children. For example, clinical and MRI findings of rhabdomyosarcoma are similar to HS (8). Specificity of the radiological features of bladder masses secondary to nonneoplastic diseases is less but still valuable in the evaluation.…”

Section: Discussionmentioning

confidence: 99%

Management of ifosfamide induced hemorrhagic cystitis in a pediatric patient with pontine glioma

Akça¹,

Akça²,

İnan³

et al. 2013

Turk J Bioch

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Bu yazıda pons gliomu nedeni ile ifosfamid kullanan ve profilaktik olarak mesna kullanmasına rağmen tedavi sonunda hemorajik sistit gelişen 5 yaşında erkek olgu sunulmuştur. Ultrason ve doppler ultrasonda mesane sağ lateral duvarda vasküler kitle izlendi. Manyetik rezonans görüntülemede(MRG) mesane sağ lateral duvarda belirgin kalınlaşma ve kontrast tutulumu mevcut iken detrusor kas intensitesi normal izlendi. Sistoskopi ve biyopsi sonrasında biyopsi sonucu 'malign transformasyon izlenmedi' şeklinde raporlanan hasta mesna daha yüksek dozda tekrar kullanılarak tedavi edildi. Böylece pediatrik hastalarda daha zor olan sistoskopinin tekrarlanmasına ve mesane irrigasyonuna ihtiyaç duyulmadı.We present the case of a 5 year old boy with hemorrhagic cystitis (HS) who diagnosed after the use of Ifosfamide due to Pons glioma. Although Mesna used for prophylaxis during treatment, developed HS at the end of the chemotherapy (CT). USG and Doppler USG showed a vascularized mass at the right wall of the bladder. Magnetic resonance imaging showed rigth bladder wall thickenign with significant enhancement and normal apperance of detrusor msucle. The mass evaluated by urologic endoscopic surgery and taken biopsy reported as "no any malign transformation". Mesna used once again in higher dosage and we did not need additional urologic endoscopic surgery or bladder irrigation which were very troublesome in pediatric age group.

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“…A characteristic histologic feature of sarcoma botryoides is the presence of a hypercellular submucosal band of spindle-shaped tumor cells termed the cambium layer, which lies just below the overlying usually intact epithelium of the involved viscus (Fig. 1e,f) (5). The region of the tumor away from the mucosal surface is of lower cellularity than the cambium layer, and shows more abundant myxoid stroma (Fig 1e).…”

Section: Discussionmentioning

confidence: 99%

“…Although the appearance of rhabdomyosarcoma on ultrasound is variable, it often appears as a polyploid mass with heterogeneous echogenicity (3,7). On computed tomography (CT), pelvic rhabdomyosarcoma also appears as a bulky mass of heterogeneous attenuation (5). CT is often used to follow and evaluate the extent of local disease as well as the degree of metastatic spread, especially pulmonary metastases.…”

Section: Discussionmentioning

confidence: 99%

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Sarcoma botryoides: MRI findings in two patients

Kobi

Khatri

Edelman

et al. 2009

Magnetic Resonance Imaging

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We report the magentic resonance (MR) findings of sarcoma botryoides in two young pediatric patients with this tumor. There has been very little literature regarding the MR appearance of this subtype of rhabdomyosarcoma. In both cases, the tumor was vaginal in origin, as would be expected in this age group. We found areas of bright T2 signal within these lesions, intermixed with areas of lower T2-signal tissue, which showed considerable enhancement. These imaging findings are reflective of the histologic architecture of these lesions, which are composed of separate myxoid and subepithelial cellular zones. In both cases, the extent of the tumor and lack of local invasion or metastatic disease were confirmed surgically, and both patients have undergone multiple postoperative MR studies that have shown lack of residual, recurrent, or metastatic disease.

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From the archives of the AFIP. Genitourinary rhabdomyosarcoma in children: radiologic-pathologic correlation.

Cited by 102 publications

References 0 publications

Sonographic Interstitial Syndrome

Sonographic Interstitial Syndrome

Management of ifosfamide induced hemorrhagic cystitis in a pediatric patient with pontine glioma

Sarcoma botryoides: MRI findings in two patients

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