“…Approximately nine chalcones have been isolated from the Chromolaena genus. These include pinocembrin chalcone (2 ′ ,4 ′ ,6 ′ -Trihydroxychalcone) from Chromolaena chasea and several compounds from Chromolaena odorata: 2 ′ ,4-dihydroxy-4 ′ ,5 ′ ,6 ′ -trimethoxy chalcone (ChDora), 2 ′ -hydroxy-3 ′ ,4,4 ′ ,5 ′ ,6 ′ -pentamethoxychalcone (Odoratin), 2 ′ -hydroxy-4,4 ′ ,5 ′ ,6 ′tetramethoxychalcone, 4,6 ′ -dihydroxy-2 ′ ,3 ′ ,4 ′ -trimethoxychalcone, 6 ′ -hydroxy-4,2 ′ ,3 ′ ,4 ′tetramethoxychalcone, 2 ′ ,4-dihydroxy-3 ′ ,4 ′ ,6 ′ -trimethoxychalcone, 2 ′ -hydroxy-3 ′ ,4,4 ′ ,6 ′tetramethoxychalcone, and 2-hydroxy-4, ′ 5, ′ 6, ′ 4,5-pentamethoxychalcone [23][24][25]. Odoratin has been observed to decrease cell viability in Cal51, HeLa, and MCF-7 breast cancer cells in a dose-dependent manner [23].…”