Front Cover: Cyclic Nigerosylnigerose Attenuates High‐Fat Diet‐Induced Fat Deposition, Colonic Inflammation, and Abnormal Glucose Metabolism and Modifies Gut Immunoglobulin a Reactivity to Commensal Bacteria

Abstract

Mol. Nutr. Food Res. 2023, 67, 202200389 DOI: https://doi.org/10.1002/mnfr.202200389 Oral administration of cyclic nigerosylnigerose (CNN), a dietary fiber, ameliorates abnormal glucose metabolism, fat deposition, and colonic inflammation in mice with high‐fat diet‐induced obesity. Impressively, the CNN‐induced effects are accompanied by an alteration of gut immunoglobulin A (IgA) reactivity to commensal gut bacteria. This is reported by Takeshi Tsuruta and co‐workers in article number 2200389.