Abstract:The Front Cover shows that like in the old French adage, “the best soups are made in the oldest pans” also “the best molecular tools are made with the oldest scaffolds”. A selection of examples in which DOTA‐type macrocycles are used as platforms for building multivalent devices, that found applications in various fields, from materials chemistry to chemical biology, is demonstrated. More information can be found in the Minireview by I. E. Valverde, A. Romieu, D. Monchaud et al.
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