Frontal Fibrosing Alopecia: An Update on Pathogenesis, Diagnosis, and Treatment

A Novel Atypical Presentation of Frontal Fibrosing Alopecia Involving the Frontoparietal Scalp

“…Frontal fibrosing alopecia (FFA) is an irreversible scarring alopecia that typically affects postmenopausal women [1,2]. Its etiology remains unknown; however, previous studies have proposed a hormonal imbalance and genetic factors may play a role [3][4][5].…”

Recalcitrant lichen planopilaris and frontal fibrosing alopecia responding to tildrakizumab

“…9 Treatment options for LPP/FFA include topical, intralesional, and systemic corticosteroids; hydroxychloroquine; antiandrogens, including finasteride and dutasteride; topical and oral retinoids and minoxidil, though there is no robust evidence of a consistent, highly effective strategy that prevents progression. 3,10 Tildrakizumab is a fully humanized monoclonal antibody that inhibits the p19 subunit of interleukin (IL)-23 and is approved by the Food and Drug Administration and European Medicines Agency for use in patients with moderate-to-severe psoriasis. Many inflammatory conditions have an up-regulation of the IL-23/IL-17 axis.…”

Case report: a rare and generalized presentation of frontal fibrosing alopecia in a man

“…Case report: a rare and generalized presentation of frontal fibrosing alopecia in a man Editor, Frontal fibrosing alopecia (FFA) is a primary cicatricial alopecia characterized by a progressive recession of the frontotemporal hairline with frequent involvement of eyebrows. 1 FFA is more frequent in postmenopausal women, but it is increasingly diagnosed among premenopausal women and men. 2 Hair involvement is also common in other sites like eyelashes, extremities and axillae.…”

“…2 Hair involvement is also common in other sites like eyelashes, extremities and axillae. 1 FFA in males frequently presents as a slight-tomoderate recession of frontotemporal hairline that could be confused with mild androgenetic alopecia. 2,3 We present the case of a 52-year-old male who presented to our department with asymptomatic slow and progressive hair loss on the scalp, beard, eyebrows and body, for 5 years.…”

“…2 Loss of hair on the occipital area has also been documented in woman. 1 Some clinical features have been associated with severe disease. In a 355-case series study, it was described that eyelash loss, facial papules and body hair involvement were more frequent in extensive cases.…”